Nearly 50 years since its potential as a fluorescent base analogue was first recognized, 2-
aminopurine (2AP) continues to be the most widely used fluorescent probe of DNA structure …

Organophosphorus Chemistry provides a comprehensive annual review of the literature.
Coverage includes phosphines and their chalcogenides, phosphonium salts, low …

Rad4/XPC recognizes diverse DNA lesions including ultraviolet-photolesions and
carcinogen-DNA adducts, initiating nucleotide excision repair. Studies have suggested that …

Cut-and-paste DNA transposons of the mariner/Tc1 family are useful tools for genome
engineering and are inserted specifically at TA target sites. A crystal structure of the mariner …

Fundamental insight into the unique fluorescence and nucleobase-mimicking properties of
the fluorescent nucleobase analogues of the tC family is not only vital in explaining the …

The HIV-1 nucleocapsid protein (NCp7) is a nucleic acid chaperone required during reverse
transcription. During the first strand transfer, NCp7 is thought to destabilize cTAR, the (−) …

The structure-and strand-specific phosphodiesterase flap endonuclease-1 (FEN1), the
prototypical 5′-nuclease, catalyzes the essential removal of 5′-single-stranded flaps …

UHRF1 plays a central role in the maintenance and transmission of epigenetic modifications
by recruiting DNMT1 to hemimethylated CpG sites via its SET and RING-associated (SRA) …

In this paper, we consider the mutagenic properties of the 2-aminopurine (2AP), which has
intrigued molecular biologists, biophysicists and physical chemists for a long time and been …

Abstract O 6-Alkylguanine-DNA alkyltransferase (AGT) repairs mutagenic O 6-alkylguanine
and O 4-alkylthymine adducts in DNA, protecting the genome and also contributing to the …