The voltage-gated potassium (Kv) channels, encoded by 40 genes, repolarize all electrically
excitable cells, including plant, cardiac, and neuronal cells. Although these genes were fully …

The classical tango is a dance characterized by a 2/4 or 4/4 rhythm in which the partners
dance in a coordinated way, allowing dynamic contact. There is a surprising similarity …

KCNQ2 and KCNQ3 potassium channels have emerged as central regulators of pyramidal
neuron excitability and spiking behavior. However, despite an abundance of evidence …

Hv1/VSOP is a dimeric voltage-gated H+ channel in which the gating of one subunit is
reportedly coupled to that of the other subunit within the dimer. The molecular basis for …

The NaChBac is a prokaryotic homologue of the voltage-gated sodium channel found in the
genome of the alkalophilic bacterium Bacillus halodurans C-125. Like a repeating cassette …

M-type K+ channels, consisting of KCNQ1–5 (Kv7. 1–7.5) subunits, form a variety of
homomeric and heteromeric channels. Whereas all the subunits can assemble into …

Mutations in KCNQ2 and KCNQ3 genes are responsible for benign familial neonatal
seizures and epileptic encephalopathies. Some of these mutations have been shown to alter …

KCNQ2 (Kv7. 2) and KCNQ3 (Kv7. 3) are the principal subunits underlying the potassium M-
current, which exerts a strong control on neuronal excitability. KCNQ3 subunits coassemble …

Abstract KCNQ1–5 (Kv7. 1–7.5) subunits assemble to form a variety of functional K+
channels in the nervous system, heart, and epithelia. KCNQ1 and KCNQ4 homomers and …

We show that the combination of an intracellular bi-partite calmodulin (CaM)-binding site
and a distant assembly region affect how an ion channel is regulated by a membrane lipid …