Mechanisms of cadmium-induced testicular injury: a risk to male fertility

W Ali, Y Ma, J Zhu, H Zou, Z Liu - Cells, 2022 - mdpi.com
Cadmium is a heavy toxic metal with unknown biological functions in the human body. Over
time, cadmium accretion in the different visceral organs (liver, lungs, kidney, and testis) is …

Molecular basis of human sperm capacitation

LC Puga Molina, GM Luque, PA Balestrini… - Frontiers in cell and …, 2018 - frontiersin.org
In the early 1950s, Austin and Chang independently described the changes that are
required for the sperm to fertilize oocytes in vivo. These changes were originally grouped …

Molecular changes and signaling events occurring in spermatozoa during epididymal maturation

MG Gervasi, PE Visconti - Andrology, 2017 - Wiley Online Library
After leaving the testis, spermatozoa have not yet acquired the ability to move progressively
and are unable to fertilize oocytes. To become fertilization competent, they must go through …

Impact of cryopreservation on spermatozoa freeze-thawed traits and relevance OMICS to assess sperm cryo-tolerance in farm animals

IM Khan, Z Cao, H Liu, A Khan, SU Rahman… - Frontiers in Veterinary …, 2021 - frontiersin.org
Sperm cryopreservation is a powerful tool for the livestock breeding program. Several
technical attempts have been made to enhance the efficiency of spermatozoa …

Mammalian sperm interactions with the female reproductive tract

SS Suarez - Cell and tissue research, 2016 - Springer
The mammalian female reproductive tract interacts with sperm in various ways in order to
facilitate sperm migration to the egg while impeding migrations of pathogens into the tract, to …

[HTML][HTML] Structurally distinct Ca2+ signaling domains of sperm flagella orchestrate tyrosine phosphorylation and motility

JJ Chung, SH Shim, RA Everley, SP Gygi, X Zhuang… - Cell, 2014 - cell.com
Spermatozoa must leave one organism, navigate long distances, and deliver their paternal
DNA into a mature egg. For successful navigation and delivery, a sperm-specific calcium …

Fertilization: a sperm's journey to and interaction with the oocyte

M Ikawa, N Inoue, AM Benham… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Mammalian fertilization comprises sperm migration through the female reproductive tract,
biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct …

A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme

KE Bernstein, FS Ong, WLB Blackwell, KH Shah… - Pharmacological …, 2013 - Elsevier
Angiotensin-converting enzyme (ACE) is a zinc-dependent peptidase responsible for
converting angiotensin I into the vasoconstrictor angiotensin II. However, ACE is a relatively …

A disintegrin and metalloprotease (ADAM): historical overview of their functions

N Giebeler, P Zigrino - Toxins, 2016 - mdpi.com
Since the discovery of the first disintegrin protein from snake venom and the following
identification of a mammalian membrane-anchored metalloprotease-disintegrin implicated …

The cell biology of mammalian fertilization

M Okabe - Development, 2013 - journals.biologists.com
Fertilization is the process by which eggs and spermatozoa interact, achieve mutual
recognition, and fuse to create a zygote, which then develops to form a new individual, thus …