New insights into balancing wound healing and scarless skin repair

S Zhou, M Xie, J Su, B Cai, J Li… - Journal of Tissue …, 2023 - journals.sagepub.com
Scars caused by skin injuries after burns, wounds, abrasions and operations have serious
physical and psychological effects on patients. In recent years, the research of scar free …

The clinical trials of mesenchymal stromal cells therapy

MR Kouchakian, N Baghban, SF Moniri… - Stem Cells …, 2021 - Wiley Online Library
Mesenchymal stromal cells (MSCs) are a heterogeneous population of adult stem cells,
which are multipotent and possess the ability to differentiate/transdifferentiate into …

Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways

R Vaka, S Parent, Y Risha, S Khan, D Courtman… - … Therapy-Nucleic Acids, 2023 - cell.com
The cell origin-specific payloads within extracellular vesicles (EVs) mediate therapeutic
bioactivity for a wide variety of stem cell types. In this study, we profiled the microRNA …

[HTML][HTML] Mechanisms underlying the cell-matrixed nerve grafts repairing peripheral nerve defects

S Wang, H Wang, P Lu, L Gong, X Gu, M Li - Bioactive Materials, 2024 - Elsevier
Decellularized extracellular matrix (dECM), with its distinct biological properties, has gained
significant attention as a natural biomaterial. Leveraging its potentials, we successfully …

Taking central nervous system regenerative therapies to the clinic: curing rodents: versus: nonhuman primates: versus: humans

M Tsintou, K Dalamagkas, N Makris - Neural Regeneration …, 2020 - journals.lww.com
The central nervous system is known to have limited regenerative capacity. Not only does
this halt the human body's reparative processes after central nervous system lesions, but it …

Muscle preservation in proximal nerve injuries: a current update

A Lysak, S Farnebo, S Geuna… - Journal of Hand …, 2024 - journals.sagepub.com
Optimal recovery of muscle function after proximal nerve injuries remains a complex and
challenging problem. After a nerve injury, alterations in the affected muscles lead to atrophy …

Tissue-regenerative potential of the secretome of γ-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis

E Simader, L Beer, M Laggner, V Vorstandlechner… - Cell death & …, 2019 - nature.com
Peripheral blood mononuclear cells (PBMCs) have been shown to produce and release a
plethora of pro-angiogenetic factors in response to γ-irradiation, partially accounting for their …

[Retracted] Long Noncoding RNA SBF2‐AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA‐520f‐3p/SMARCD1 Axis

B Han, M Yang, Q Liu, G Wang, J Hou - Disease Markers, 2022 - Wiley Online Library
Abdominal aortic aneurysm (AAA) is a chronic vascular inflammatory disease. The
regulatory mechanisms during AAA formation remain unclear. Bone marrow stem cells …

Peripheral nerve regeneration using different germ layer‐derived adult stem cells in the past decade

Y Li, Y Kamei, M Kambe, K Ebisawa… - Behavioural …, 2021 - Wiley Online Library
Peripheral nerve injuries (PNIs) are some of the most common types of traumatic lesions
affecting the nervous system. Although the peripheral nervous system has a higher …

[HTML][HTML] Effect of treadmill exercise and bone marrow stromal cell engraftment on activation of BDNF-ERK-CREB signaling pathway in the crushed sciatic nerve

TB Seo, YH Cho, H Sakong, YP Kim - Journal of exercise …, 2021 - ncbi.nlm.nih.gov
The effect of combined approach of exercise training and bone marrow stromal cell (BMSC)
engraftment on activation of brain-derived neurotrophic factor (BDNF)-extracellular signal …