Misuse/over use of antibiotics increases the threats to human health since this is a main
reason behind evolution of antibiotic resistant bacterial pathogens. However, metals such as …

Environmental influences on antibiotic activity and resistance can wreak havoc with in vivo
antibiotic efficacy and, ultimately, antimicrobial chemotherapy. In nature, bacteria encounter …

Lung cancer is often asymptomatic or causes only nonspecific symptoms in its early stages.
Early detection represents one of the most promising approaches to reduce the growing …

Lung cancer is the leading cause of cancer death for both men and women worldwide.
Since most of the symptoms found for lung cancer are nonspecific, diagnosis is mostly done …

The discovery of disease-specific biomarkers in oral fluids has revealed a new dimension in
molecular diagnostics. Recent studies have reported the mechanistic involvement of tumor …

Background Streptococcus pneumoniae, the pneumococcus, is the main etiological agent of
pneumonia. Pneumococcal infection is initiated by bacterial adherence to lung epithelial …

The opportunistic pathogen Pseudomonas aeruginosa responds to zinc, cadmium and
cobalt by way of the CzcRS two-component system. In presence of these metals the …

Lung diseases, such as asthma, chronic obstructive pulmonary diseases (COPD), and cystic
fibrosis (CF), are among the leading causes of mortality and morbidity globally. They …

The cystic fibrosis (CF) lung contains thick mucus colonized by opportunistic pathogens
which adapt to the CF lung environment over decades. The difficulty associated with …

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen that is
refractory to a variety of current antimicrobial therapeutic regimens. Complicating treatment …