Non-invasive biomarkers for immunotherapy in patients with hepatocellular carcinoma: current knowledge and future perspectives

M Pallozzi, N Di Tommaso, V Maccauro, F Santopaolo… - Cancers, 2022 - mdpi.com
Simple Summary The search for non-invasive biomarkers is a hot topic in modern oncology,
since a tissue biopsy has significant limitations in terms of cost and invasiveness. The …

The Role of Bifidobacterium in Liver Diseases: A Systematic Review of Next-Generation Sequencing Studies

GH Hizo, PH Rampelotto - Microorganisms, 2023 - mdpi.com
The physiopathology of liver diseases is complex and can be caused by various factors.
Bifidobacterium is a bacterial genus commonly found in the human gut microbiome and has …

[HTML][HTML] Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function

YW Zhang, MM Cao, YJ Li, PP Lu, GC Dai… - Journal of orthopaedic …, 2022 - Elsevier
Background Osteoporosis (OP) is a systemic metabolic bone disease characterized by
decreased bone mass and destruction of bone microstructure, which tends to result in …

Isoflavone diet ameliorates experimental autoimmune encephalomyelitis through modulation of gut bacteria depleted in patients with multiple sclerosis

SN Jensen, NM Cady, SK Shahi, SR Peterson… - Science …, 2021 - science.org
The gut microbiota is a potential environmental factor that influences the development of
multiple sclerosis (MS). We and others have demonstrated that patients with MS and healthy …

Breast cancer patients from the Midwest region of the United States have reduced levels of short-chain fatty acid-producing gut bacteria

RL Shrode, JE Knobbe, N Cady, M Yadav, J Hoang… - Scientific reports, 2023 - nature.com
As geographical location can impact the gut microbiome, it is important to study region-
specific microbiome signatures of various diseases. Therefore, we profiled the gut …

Assisted selection of biomarkers by linear discriminant analysis effect size (LEfSe) in microbiome data

F Chang, S He, C Dang - JoVE (Journal of Visualized Experiments), 2022 - jove.com
There is growing attention toward closed biological genomes in the environment and in
health. To explore and reveal the intergroup differences among different samples or …

Obesity induced gut dysbiosis contributes to disease severity in an animal model of multiple sclerosis

SK Shahi, S Ghimire, P Lehman… - Frontiers in …, 2022 - frontiersin.org
Background Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the
CNS. The etiology of MS is complex, and results from the interaction of multiple …

Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer

J Chau, M Yadav, B Liu, M Furqan, Q Dai, S Shahi… - BMC cancer, 2021 - Springer
Background Though the gut microbiome has been associated with efficacy of
immunotherapy (ICI) in certain cancers, similar findings have not been identified for …

Gut microbiota regulation of inflammatory cytokines and microRNAs in diabetes-associated cognitive dysfunction

H Huang, T Zhao, J Li, J Shen, R Xiao, W Ma - Applied Microbiology and …, 2023 - Springer
Type 2 diabetes mellitus (T2DM) has a major comorbidity known as diabetes-associated
cognitive dysfunction (DACD). Studies have demonstrated that the gut microbiota is crucial …

Low-dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis

PC Lehman, N Cady, S Ghimire, SK Shahi… - Environmental …, 2023 - Elsevier
The widespread use of glyphosate, a broad-spectrum herbicide, has resulted in significant
human exposure, and recent studies have challenged the notion that glyphosate is safe for …