Objective Nosebleed, also known as epistaxis, is a common problem that occurs at some
point in at least 60% of people in the United States. While the majority of nosebleeds are …

Hereditary haemorrhagic telangiectasia, inherited as an autosomal dominant trait, affects
approximately 1 in 5000 people. The abnormal vascular structures in HHT result from …

Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant
disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of …

Background HHT is an autosomal dominant disease with an estimated prevalence of at least
1/5000 which can frequently be complicated by the presence of clinically significant …

Context The only treatment available to restore normal cardiac output in patients with
hereditary hemorrhagic telangiectasia (HHT) and cardiac failure is liver transplant. Anti …

Introduction: Rare diseases (RDs) are a severe, chronic, degenerative and often life-
threatening group of conditions affecting more than 30 million people in Europe. Their …

Quality of life (QoL) refers to an individual's sense of overall well‐being encompassing
physical, psychological, emotional, social, and spiritual dimensions. Although genetics …

Abstract Objectives/Hypothesis: Hereditary hemorrhagic telangiectasia (HHT)‐related
epistaxis leads to alterations in social functioning and quality of life. Although more than …

Hereditary haemorrhagic telangiectasia (HHT) is a vascular dysplasia inherited as an
autosomal dominant trait and caused by loss-of-function pathogenic variants in genes …

Objective To present a multiyear clinical experience with intravenous bevacizumab for the
management of severe gastrointestinal bleeding and/or epistaxis in patients with hereditary …