Proteinopathies: deciphering physiology and mechanisms to develop effective therapies for neurodegenerative diseases

G Chopra, S Shabir, S Yousuf, S Kauts, SA Bhat… - Molecular …, 2022 - Springer
Neurodegenerative diseases (NDs) are a cluster of diseases marked by progressive
neuronal loss, axonal transport blockage, mitochondrial dysfunction, oxidative stress …

Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster

F Ponton, MP Chapuis, M Pernice, GA Sword… - Journal of insect …, 2011 - Elsevier
Drosophila melanogaster is one of the most important genetic models and techniques such
as reverse transcription quantitative real-time PCR (RT-qPCR) are being employed …

Ameliorative Role of Nutraceuticals on Neurodegenerative Diseases Using the Drosophila melanogaster as a Discovery Model to Define Bioefficacy

R Himalian, SK Singh, MP Singh - Journal of the American …, 2022 - Taylor & Francis
Neurodegeneration is the destruction of neurons, and once the neurons degenerate they
can't revive. This is one of the most concerned health conditions among aged population …

Hydrogen sulfide exposure triggers chicken trachea inflammatory injury through oxidative stress-mediated FOS/IL8 signaling

M Chen, X Li, Q Shi, Z Zhang, S Xu - Journal of hazardous materials, 2019 - Elsevier
Hydrogen sulfide (H 2 S) is well known to cause irritation and damage to airway following
inhalation, but the mechanism by which H 2 S contributes to airway toxicity is unclear. In …

Ethnopharmacological Effects of Urtica dioica, Matricaria chamomilla, and Murraya koenigii on Rotenone-Exposed D. melanogaster: An Attenuation of Cellular …

S Shabir, S Yousuf, SK Singh, E Vamanu, MP Singh - Antioxidants, 2022 - mdpi.com
Natural antioxidants derived from plants have been proven to have significant inhibitory
effects on the free radicals of living organisms during actively metabolization. Excessive …

Toxicological Profile of Polyethylene Terephthalate (PET) Microplastic in Ingested Drosophila melanogaster (Oregon R+) and Its Adverse Effect on Behavior and …

S Kauts, Y Mishra, S Yousuf, R Bhardwaj, SK Singh… - Toxics, 2023 - mdpi.com
Microplastics are readily available in the natural environment. Due to the pervasiveness of
microplastic pollution, its effects on living organisms necessitate further investigation. The …

In vivo assessment of CdSe–ZnS quantum dots: coating dependent bioaccumulation and genotoxicity

A Galeone, G Vecchio, MA Malvindi, V Brunetti… - Nanoscale, 2012 - pubs.rsc.org
Semiconductor nanocrystals, or Quantum Dots (QDs), have gained considerable attention
due to their unique size-dependent optical and electronic properties that make them …

Synthesis of green engineered silver nanoparticles through Urtica dioica: An inhibition of microbes and alleviation of cellular and organismal toxicity in Drosophila …

MP Singh, S Shabir, AS Deopa, SR Raina, F Bantun… - Antibiotics, 2022 - mdpi.com
Plant fractions have a diversity of biomolecules that can be used to make complicated
reactions for the bioactive fabrication of metal nanoparticles (NPs), in addition to being …

Hsp70 overexpression in Drosophila hemocytes attenuates benzene‐induced immune and developmental toxicity via regulating ROS/JNK signaling pathway

LC D'Souza, S Dwivedi, F Raihan… - Environmental …, 2022 - Wiley Online Library
Benzene, a ubiquitous environmental chemical, is known to cause immune dysfunction and
developmental defects. This study aims to investigate the relation between benzene …

Mixture and individual effects of benzene, toluene, and formaldehyde in zebrafish (Danio rerio) development: Metabolomics, epigenetics, and behavioral approaches

N Chatterjee, C Kim, J Im, S Kim, J Choi - Environmental Toxicology and …, 2023 - Elsevier
In this study, we aimed to investigate the potential hazards of volatile organic compounds
(VOCs) on the development of zebrafish. To this end, zebrafish embryos were exposed in …