The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Cardiovascular diseases have become the leading cause of human death. Aging is an
independent risk factor for cardiovascular diseases. Cardiac aging is associated with …

Objective Ferroptosis is indicated in cardiovascular diseases. Given the prominent role of
mitophagy in the governance of ferroptosis and our recent finding for FUN14 domain …

Physical exercise promotes cardiorespiratory fitness, and is considered the mainstream of
non-pharmacological therapies along with lifestyle modification for various chronic diseases …

Defective mitophagy is causally linked to obesity complications. Here, we identified an
interaction between mitophagy protein FUNDC1 (FUN14 domain containing 1) and receptor …

Recent evidence shows a close link between Parkinson's disease (PD) and cardiac
dysfunction with limited treatment options. Mitophagy plays a crucial role in the control of …

Advanced aging exhibits altered cardiac geometry and function involving mitochondrial
anomaly. Natural compounds display promises in the regulation of cardiac homeostasis via …

In patients with sepsis, lipopolysaccharide (LPS) from the outer membrane of gram-negative
bacteria triggers cardiac dysfunction and heart failure, but target therapy for septic …

High fat diet intake contributes to undesired cardiac geometric and functional changes
although the underlying mechanism remains elusive. Akt and AMPK govern to cardiac …

Although androgen deprivation therapy may initially be effective in prostate cancer, the
disease can gradually progress to castration-resistant prostate cancer, at which point …