The treatment of cognitive, behavioural and motor impairments from brain injury and neurodegenerative diseases through cannabinoid system modulation—evidence …

D Calina, AM Buga, M Mitroi, A Buha… - Journal of Clinical …, 2020 - mdpi.com
Neurological disorders such as neurodegenerative diseases or traumatic brain injury are
associated with cognitive, motor and behavioural changes that influence the quality of life of …

Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes

TY Kong, JH Kim, DK Kim, HS Lee - Archives of pharmacal research, 2018 - Springer
Synthetic cannabinoids, a new class of psychoactive substances, are potent agonists of
cannabinoid receptors, which mimic the psychoactive effects of the principal psychoactive …

Synthetic cannabinoids and cardiac arrhythmia risk: review of the literature

HM Ozturk, E Yetkin, S Ozturk - Cardiovascular toxicology, 2019 - Springer
Synthetic cannabinoids (SCBs) are widely used recreational substances especially among
adults. Although they have been considered as safe during the marketing process, our …

Short-and long-term exposures of the synthetic cannabinoid 5F-APINAC induce metabolomic alterations associated with neurotransmitter systems and embryotoxicity …

PA Markin, A Brito, NE Moskaleva, F Tagliaro… - … and Physiology Part C …, 2021 - Elsevier
Introduction Synthetic cannabinoids are abused substances with strong psychoactive
effects. Little is known about the effects on neurotransmission and the toxicity of the second …

Acute intoxication caused by three common synthetic cannabinoids: the experience of a large, urban, tertiary care hospital

N Shopan, D Scolnik, E Hassoun, A Firsow… - The American Journal of …, 2023 - Elsevier
Background Synthetic cannabinoids (SC) are chemical substances, which activate
cannabinoid receptors in a similar fashion to tetrahydrocannabinol, but with increased …

Highly sensitive screening and analytical characterization of synthetic cannabinoids in nine different herbal mixtures

VL Alves, JL Gonçalves, J Aguiar, MJ Caldeira… - Analytical and …, 2021 - Springer
The popularity of new psychoactive substances among drug users has become a public
health concern worldwide. Among them, synthetic cannabinoids (SCs) represent the largest …

Pharmacotherapy of patients taking new psychoactive substances: a systematic review and analysis of case reports

M Ordak, A Zmysłowska, M Bielski, D Rybak… - Frontiers in …, 2021 - frontiersin.org
Background: In recent years, an increase in the frequency of hospitalizations of patients
taking newer and newer psychoactive substances has been observed around the world …

Review of synthetic cannabinoids on the illicit drug market

MA ElSohly, S Ahmed, SW Gul, W Gul - Critical issues in alcohol and drugs …, 2019 - Elsevier
Cannabimimetics (synthetic cannabinoids) exhibit agonistic activity on the two cannabinoid
re-ceptors, CB1 and CB2 but have no structural similarity with the active compound of …

In vitro inhibitory effects of synthetic cannabinoid EAM-2201 on cytochrome p450 and udp-glucuronosyltransferase enzyme activities in human liver microsomes

TY Kong, SS Kwon, JC Cheong, HS Kim, JY Kim… - Molecules, 2018 - mdpi.com
EAM-2201, a synthetic cannabinoid, is a potent agonist of the cannabinoid receptors that is
widely abused as an illicit recreational drug in combination with other drugs. To evaluate the …

[HTML][HTML] Cannabis Use and Its Multifaceted Impact on the Genitourinary System: A Scoping Review of the Literature

NA Bandara, D Lalkiya… - Journal of …, 2024 - xiahepublishing.com
Methods A scoping review search was undertaken on Embase, Medline, and Web of
Science. There were no date restrictions applied. Studies that included data from humans …