Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …

This review will describe the structure and function of the eosinophil. The roles of several
relevant cell surface molecules and receptors will be discussed. We will also explore the …

Eosinophils are a minority circulating granulocyte classically viewed as being involved in
host defense against parasites and promoting allergic reactions. However, a series of new …

Eosinophils are innate immune leukocytes found in relatively low numbers within the blood.
Terminal effector functions of eosinophils, deriving from their capacity to release their …

Surprisingly, the role (s) of eosinophils in health and disease is often summarized by
clinicians and basic research scientists as a pervasive consensus opinion first learned in …

The respective life histories of human subjects and mice are well defined and describe a
unique story of evolutionary conservation extending from sequence identity within the …

The kynurenine pathway (KP) is highly regulated in the immune system, where it promotes
immunosuppression in response to infection or inflammation. Indoleamine 2, 3-dioxygenase …

Eosinophils, innate immune leukocytes elicited by Th2 cells, have long been associated with
the effector arm of Th2 immune responses. However, accumulating data over the past …

Eosinophils are granulocytes primarily associated with TH2 responses to parasites or
immune hyper-reactive states, such as asthma, allergies, or eosinophilic esophagitis …

Eosinophils perform numerous tasks. They are involved in inflammatory reactions
associated with innate immune defence against parasitic infections and are also involved in …