The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …

Next-generation sequencing (NGS) is a method that allows for high-throughput, massively
parallel sequencing of thousands to billions of DNA fragments independently and …

Background The role of the human microbiome in health and disease is an emerging and
important area of research; however, there is a concern that African populations are under …

West Nile Virus (WNV) is an arthropod-borne flavivirus whose zoonotic cycle includes both
mosquitoes and birds as amplifiers and humans and horses as dead-end hosts. In recent …

Background Metagenomic next generation sequencing (mNGS) is becoming increasingly
available for pathogen detection directly from clinical specimens. These tests use target …

There is a need in clinical microbiology and public health for assays that enable sensitive
and rapid detection of infectious agents. Next Generation Sequencing (NGS) is increasingly …

Background Metagenomic next-generation sequencing (mNGS) has emerged as a
promising technology that enables pan-pathogen detection from any source. However …

We report a platform that increases the sensitivity of high-throughput sequencing for
detection and characterization of bacteria, virulence determinants, and antimicrobial …

A body temperature> 38.3° C that lasts≥ 3 weeks and lacks a clear diagnosis after 1 week
of standard hospital examination and treatment is called “fever of unknown origin”(FUO) …

Objectives Many patients with meningitis have no aetiology identified leading to
unnecessary antimicrobials and prolonged hospitalisation. We used viral capture …