Potential activity of traditional Chinese medicine against ulcerative colitis: a review

Y Liu, BG Li, YH Su, RX Zhao, P Song, H Li… - Journal of …, 2022 - Elsevier
Ethnic pharmacological relevance Plant materials are used as complementary and
alternative therapies all over the world for the treatment of various diseases. Ulcerative …

Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Self-nanoemulsifying drug delivery system (SNEDDS) mediated improved oral bioavailability of thymoquinone: optimization, characterization, pharmacokinetic, and …

C Rathore, C Hemrajani, AK Sharma, PK Gupta… - Drug Delivery and …, 2023 - Springer
Thymoquinone (TQ) is an antioxidant, anti-inflammatory, and hepatoprotective compound
obtained from the black seed oil of Nigella sativa. However, high hydrophobicity, instability …

Lipid based drug delivery systems for oral, transdermal and parenteral delivery: recent strategies for targeted delivery consistent with different clinical application

AK Srivastav, S Karpathak, MK Rai, D Kumar… - Journal of Drug Delivery …, 2023 - Elsevier
Lipid based drug delivery systems (LBDDS) are valuable and biocompatible nano-carriers
for the vehiculation and potential delivery of various hydrophilic, hydrophobic, or amphiphilic …

New insights of oral colonic drug delivery systems for inflammatory bowel disease therapy

AH Teruel, I Gonzalez-Alvarez, M Bermejo… - International journal of …, 2020 - mdpi.com
Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of
inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug …

[HTML][HTML] Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer's disease via inhibiting neuropathology and modulating gut microbiota

C Qu, QP Li, ZR Su, SP Ip, QJ Yuan, YL Xie… - Journal of advanced …, 2022 - Elsevier
Introduction Honokiol (HO) exerts neuroprotective effects in several animal models of
Alzheimer's disease (AD), but the poor dissolution hampers its bioavailability and …

Oral delivery of pterostilbene by L-arginine-mediated “nano-bomb” carrier for the treatment of ulcerative colitis

W Wei, Y Zhang, R Li, Y Cao, X Yan, Y Ma… - International Journal …, 2022 - Taylor & Francis
Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) of
unknown aetiology affecting the colon and rectum. Pterostilbene (PS) has been reported as …

[HTML][HTML] Targeting Trop2 by Bruceine D suppresses breast cancer metastasis by blocking Trop2/β-catenin positive feedback loop

W Tang, Y Hu, K Tu, Z Gong, M Zhu, T Yang… - Journal of Advanced …, 2024 - Elsevier
Introduction Tumor-associated calcium signal transducer 2 (Trop2) has been used as a
transport gate for cytotoxic agents into cells in antibody–drug conjugate designs because of …

Biomaterial-based strategies for immunomodulation in IBD: current and future scenarios

C Jori, AA Chaudhary, S Rashid, MAM Ali… - Journal of Materials …, 2023 - pubs.rsc.org
Instinctive gastrointestinal inflammatory conditions with persistent intestinal inflammation are
known as “inflammatory bowel diseases”(IBDs). IBDs are growing progressively common …