Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …

Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

Injectable hydrogels have gained popularity as a vehicle for the delivery of cells, growth
factors, and other molecules to localize and improve their retention at the injection site, as …

Pluripotent stem-cell-derived cardiomyocytes (PSC-CMs) provide an unprecedented
opportunity to study human heart development and disease, but they are functionally and …

Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …

Consumption of high-quality animal protein plays an important role in improving human
nutrition, growth, development, and health. With an exponential growth of the global …

Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

In the present study, a novel biodegradable Zn-0.8 Cu coronary artery stent was fabricated
and implanted into porcine coronary arteries for up to 24 months. Micro-CT analysis showed …

The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Rabbit, a member of the Lagomorpha order, is the closest phylogenetic relative to humans,
next to primates. It possesses greater acceptability as a laboratory mammal than primates in …