GSK3 has been implicated for years in the regulation of inflammation and addressed in a
plethora of scientific reports using a variety of experimental (disease) models and …

Leishmania spp. are intracellular parasitic protozoa responsible for a group of neglected
tropical diseases, endemic in 98 countries around the world, called leishmaniasis. These …

Leishmaniasis is a major health problem that affects more than 300 million people
throughout the world. The morbidity associated with the disease causes serious economic …

Around 25% of the global population suffer from one or more parasitic infections, of which
food-and vector-borne parasitic zoonotic diseases are a major concern. Additionally …

Nod-like receptors (NLRs) have gained attention in recent years because of the ability of
some family members to assemble into a multimeric protein complex known as the …

Cytokines play crucial roles in commencing and coordinating the organized recruitment and
activation of immune cells during infection. These molecular regulators play an important …

Abstract Treatment of visceral leishmaniasis (VL) is compromised by drug toxicity, high cost
and/or the emergence of resistant strains. Though canine vaccines are available, there are …

The notion that previous infection by Leishmania spp. in endemic areas leads to robust anti-
Leishmania immunity, supports vaccination as a potentially effective approach to prevent …

Leishmaniasis is a vector-borne disease caused by protozoan parasites from the genus
Leishmania. The most severe form of disease is visceral leishmaniasis (VL), which is fatal if …

Immunometabolic framework provides a way to understand the immune regulation via cell
intrinsic metabolic fluxes and metabolites during infections, tumors, and inflammatory …