AmpC β-lactamases

GA Jacoby - Clinical microbiology reviews, 2009 - Am Soc Microbiol
AmpC β-lactamases are clinically important cephalosporinases encoded on the
chromosomes of many of the Enterobacteriaceae and a few other organisms, where they …

The new β-lactamases

GA Jacoby, LS Munoz-Price - New England Journal of Medicine, 2005 - Mass Medical Soc
The β-lactamases are the major bacterial defense of gram-negative bacteria against β-
lactam antibiotics. This review details the many types of β-lactamases, explains how they …

Extraintestinal Pathogenic Escherichia coli: A Combination of Virulence with Antibiotic Resistance

JDD Pitout - Frontiers in microbiology, 2012 - frontiersin.org
Escherichia coli represents an incredible versatile and diverse enterobacterial species and
can be subdivided into the following;(i) intestinal non-pathogenic, commensal isolates.(ii) …

Extended-spectrum-β-lactamase, AmpC, and carbapenemase issues

KS Thomson - Journal of clinical microbiology, 2010 - Am Soc Microbiol
Optimal use of microbiology laboratories is essential to combat the spread of multiply
antibiotic-resistant pathogens. This is vital for patient care, as advocated by Jarvis in …

Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials

AK Thabit, JL Crandon, DP Nicolau - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Antimicrobial resistance is a well-recognized global threat; thus, the
development of strong infection control policies coupled with antimicrobial stewardship …

Broad-spectrum β-lactamases among Enterobacteriaceae of animal origin: molecular aspects, mobility and impact on public health

A Smet, A Martel, D Persoons, J Dewulf… - FEMS microbiology …, 2010 - academic.oup.com
Broad-spectrum β-lactamase genes (coding for extended-spectrum β-lactamases and AmpC
β-lactamases) have been frequently demonstrated in the microbiota of food-producing …

Creeping baselines and adaptive resistance to antibiotics

L Fernández, EBM Breidenstein… - Drug Resistance Updates, 2011 - Elsevier
The introduction of antimicrobial drugs in medicine gave hope for a future in which all
infectious diseases could be controlled. Decades later it appears certain this will not be the …

AmpC Disk Test for Detection of Plasmid-Mediated AmpC β-Lactamases in Enterobacteriaceae Lacking Chromosomal AmpC β-Lactamases

JA Black, ES Moland, KS Thomson - Journal of clinical …, 2005 - Am Soc Microbiol
Although plasmid-mediated AmpC β-lactamases were first reported in the late 1980s, many
infectious disease personnel remain unaware of their clinical importance. These enzymes …

Phenotypic detection of carbapenem-susceptible metallo-β-lactamase-producing gram-negative bacilli in the clinical laboratory

C Franklin, L Liolios, AY Peleg - Journal of clinical microbiology, 2006 - Am Soc Microbiol
Rapid detection of metallo-β-lactamase (MBL)-producing gram-negative pathogens is
critical to prevent their widespread dissemination. Thus far, no standardized phenotypic …

Extraintestinal pathogenic Escherichia coli: an update on antimicrobial resistance, laboratory diagnosis and treatment

JDD Pitout - Expert review of anti-infective therapy, 2012 - Taylor & Francis
Escherichia coli remains one of the most frequent causes of nosocomial and community-
acquired bacterial infections including urinary tract infections, enteric infections and systemic …