[HTML][HTML] Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review

UN Das - Journal of advanced research, 2018 - Elsevier
Our body is endowed with several endogenous anti-microbial compounds such as
interferon, cytokines, free radicals, etc. However, little attention has been paid to the …

[HTML][HTML] Role of food nutrients and supplementation in fighting against viral infections and boosting immunity: A review

R Thirumdas, A Kothakota, R Pandiselvam… - Trends in food science & …, 2021 - Elsevier
Background The viral infections can be highly contagious and easily transmissible, which
even can lead to a pandemic, like the recent COVID-19 outbreak, causing massive deaths …

Can bioactive lipids inactivate coronavirus (COVID-19)?

UN Das - Archives of medical research, 2020 - Elsevier
SARS-CoV-2, SARS and MERS are all enveloped viruses that can cause acute respiratory
syndrome. Arachidonic acid (AA) and other unsaturated fatty acids (especially …

Lipoxin mimetics and the resolution of inflammation

C Godson, P Guiry, E Brennan - Annual Review of …, 2023 - annualreviews.org
Inflammation and its timely resolution are critical to ensure effective host defense and
appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation …

Resolution of cancer-promoting inflammation: a new approach for anticancer therapy

Q Zhang, B Zhu, Y Li - Frontiers in immunology, 2017 - frontiersin.org
Inflammation is a protective response that eliminates harmful stimuli and restores tissue
homeostasis, whereas the failure to resolve inflammation leads to the development of …

“Cell membrane theory of senescence” and the role of bioactive lipids in aging, and aging associated diseases and their therapeutic implications

UN Das - Biomolecules, 2021 - mdpi.com
Lipids are an essential constituent of the cell membrane of which polyunsaturated fatty acids
(PUFAs) are the most important component. Activation of phospholipase A2 (PLA2) induces …

Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: Mechanisms and development

A Yang, Y Wu, G Yu, H Wang - Respiratory Research, 2021 - Springer
Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Formyl peptide receptor type 2 agonists to kick‐start resolution pharmacology

M Perretti, C Godson - British Journal of Pharmacology, 2020 - Wiley Online Library
One way to develop innovative approaches for the treatment of chronic diseases is to exploit
the biology of the resolution of inflammation. With this terminology, we identify the integrated …

Specialized Pro-Resolving Lipid Mediators: Endogenous Roles and Pharmacological Activities in Infections

FS Rasquel-Oliveira, MDV Silva, G Martelossi-Cebinelli… - Molecules, 2023 - mdpi.com
During an infection, inflammation mobilizes immune cells to eliminate the pathogen and
protect the host. However, inflammation can be detrimental when exacerbated and/or …

Specialized pro‐resolving mediators: biosynthesis and biological role in bacterial infections

PM Jordan, O Werz - The FEBS journal, 2022 - Wiley Online Library
Acute inflammation caused by bacterial infections is an essential biological defence
mechanism of the host in order to neutralize and clear the invaders and to return to …