Background The viral infections can be highly contagious and easily transmissible, which even can lead to a pandemic, like the recent COVID-19 outbreak, causing massive deaths …
UN Das - Archives of medical research, 2020 - Elsevier
SARS-CoV-2, SARS and MERS are all enveloped viruses that can cause acute respiratory syndrome. Arachidonic acid (AA) and other unsaturated fatty acids (especially …
C Godson, P Guiry, E Brennan - Annual Review of …, 2023 - annualreviews.org
Inflammation and its timely resolution are critical to ensure effective host defense and appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation …
Q Zhang, B Zhu, Y Li - Frontiers in immunology, 2017 - frontiersin.org
Inflammation is a protective response that eliminates harmful stimuli and restores tissue homeostasis, whereas the failure to resolve inflammation leads to the development of …
Lipids are an essential constituent of the cell membrane of which polyunsaturated fatty acids (PUFAs) are the most important component. Activation of phospholipase A2 (PLA2) induces …
A Yang, Y Wu, G Yu, H Wang - Respiratory Research, 2021 - Springer
Inflammation is an essential mechanism of various diseases. The development and resolution of inflammation are complex immune-modulation processes which induce the …
M Perretti, C Godson - British Journal of Pharmacology, 2020 - Wiley Online Library
One way to develop innovative approaches for the treatment of chronic diseases is to exploit the biology of the resolution of inflammation. With this terminology, we identify the integrated …
During an infection, inflammation mobilizes immune cells to eliminate the pathogen and protect the host. However, inflammation can be detrimental when exacerbated and/or …
PM Jordan, O Werz - The FEBS journal, 2022 - Wiley Online Library
Acute inflammation caused by bacterial infections is an essential biological defence mechanism of the host in order to neutralize and clear the invaders and to return to …