Personalized medicine using DNA biomarkers: a review
A Ziegler, A Koch, K Krockenberger, A Großhennig - Human genetics, 2012 - Springer
Biomarkers are of increasing importance for personalized medicine, with applications
including diagnosis, prognosis, and selection of targeted therapies. Their use is extremely …
including diagnosis, prognosis, and selection of targeted therapies. Their use is extremely …
based colorimetric sensors for point-of-care testing
A Ko, C Liao - Analytical Methods, 2023 - pubs.rsc.org
By eliminating the need for sample transportation and centralized laboratory analysis, point-
of-care testing (POCT) enables on-the-spot testing, with results available within minutes …
of-care testing (POCT) enables on-the-spot testing, with results available within minutes …
SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway
We investigated the oncogenic role of SETDB1, focusing on non‐small cell lung cancer
(NSCLC), which has high expression of this protein. A total of 387 lung cancer cases were …
(NSCLC), which has high expression of this protein. A total of 387 lung cancer cases were …
N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 is overexpressed in cancer and promotes a pro-migratory and pro-metastatic phenotype
Abstract N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 (NAALADL2) is a member of the
glutamate carboxypeptidase II family, best characterized by prostate-specific membrane …
glutamate carboxypeptidase II family, best characterized by prostate-specific membrane …
Secretion of pro-oncogenic AGR2 protein in cancer
NA Moidu, NSA Rahman, SE Syafruddin, TY Low… - Heliyon, 2020 - cell.com
Abstract Anterior gradient-2 (AGR2) protein mediates the formation, breakage and
isomerization of disulphide bonds during protein maturation in the endoplasmic reticulum …
isomerization of disulphide bonds during protein maturation in the endoplasmic reticulum …
Androgen-regulated metabolism and biosynthesis in prostate cancer
SJ Barfeld, HM Itkonen, A Urbanucci… - Endocrine-related …, 2014 - erc.bioscientifica.com
Germline BRCA2 mutations are the first known cause of inherited (familial) pancreatic ductal
adenocarcinoma (PDAC). This tumor is the third most frequent cancer in carriers of germline …
adenocarcinoma (PDAC). This tumor is the third most frequent cancer in carriers of germline …
[HTML][HTML] From development to cancer-an ever-increasing role of AGR2
D Jach, Y Cheng, F Prica, L Dumartin… - American journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Anterior gradient 2, AGR2, is a small, 20 kDa protein that plays a vital role in
oxidative protein folding in the endoplasmic reticulum. AGR2 is involved in several signal …
oxidative protein folding in the endoplasmic reticulum. AGR2 is involved in several signal …
AGR2, ERp57/GRP58, and some other human protein disulfide isomerases
SS Shishkin, LS Eremina, LI Kovalev… - Biochemistry (Moscow …, 2013 - Springer
This review considers the major features of human proteins AGR2 and ERp57/GRP58 and
of other members of the protein disulfide isomerase (PDI) family. The ability of both AGR2 …
of other members of the protein disulfide isomerase (PDI) family. The ability of both AGR2 …
[HTML][HTML] Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion
Anterior gradient 2 (AGR2) is a normal endoplasmic reticulum protein that has two important
abnormal functions, amphibian limb regeneration and human cancer metastasis promotion …
abnormal functions, amphibian limb regeneration and human cancer metastasis promotion …
Single domain antibodies as new biomarker detectors
Biomarkers are defined as indicators of biological processes, pathogenic processes, or
pharmacological responses to a therapeutic intervention. Biomarkers have been widely …
pharmacological responses to a therapeutic intervention. Biomarkers have been widely …