B cells have long played an enigmatic role in the scenario of multiple sclerosis
pathogenesis. This review summarizes recent progress in our understanding of B‐cell …

A variety of cellular and humoral immunological abnormalities have been observed in
multiple sclerosis (MS). In the past few years, several lines of evidence converged to imply …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system white
matter. The association of the disease with MHC genes, the inflammatory white matter …

A cardinal feature of multiple sclerosis (MS) is the persistent intrathecal synthesis of
antibodies. Our previous finding that a large fraction of B cells infiltrating the MS brain are …

Introduction Fuchs' heterochromic cyclitis (FHC) is a common intraocular disease of
uncertain etiology that has recently been related to rubella virus (RV) infection. Methods We …

The pathogenic events in multiple sclerosis (MS) that result in immune cell infiltration,
multifocal demyelination and axonal loss have been focused by the strong impact of the …

Introduction: Intrathecal B-lymphocyte activation is a hallmark of multiple sclerosis (MS), a
multi-factorial inflammatory-demyelinating disease of the central nervous system. Such …

Abstract Human herpesvirus 6 (HHV–6) is one of many infectious agents that have been
implicated in the pathogenesis of multiple sclerosis (MS). Intrathecal immunoglobulin (Ig) …

Chronic intrathecal immunoglobulin (Ig) production is a hallmark of multiple sclerosis
characterized by the presence of oligoclonal IgGs and, in addition, polyspecific recognition …

Progressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease due
to JC virus (JCV) replication in the brain. PML classically occurs in patients with severe …