Gallic acid for cancer therapy: Molecular mechanisms and boosting efficacy by nanoscopical delivery

M Ashrafizadeh, A Zarrabi, S Mirzaei, F Hashemi… - Food and Chemical …, 2021 - Elsevier
Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

An update on the potential mechanism of gallic acid as an antibacterial and anticancer agent

S Keyvani‐Ghamsari, M Rahimi… - Food Science & …, 2023 - Wiley Online Library
Drug resistance to antibacterial and anticancer drugs is one of the most important global
problems in the treatment field that is constantly expanding and hinders the recovery and …

[HTML][HTML] Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer

M Haider, KZ Zaki, MR El Hamshary, Z Hussain… - Journal of advanced …, 2022 - Elsevier
Background Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …

[HTML][HTML] Dendrimers as nanocarriers for the delivery of drugs obtained from natural products

H An, X Deng, F Wang, P Xu, N Wang - Polymers, 2023 - mdpi.com
Natural products have proven their value as drugs that can be therapeutically beneficial in
the treatment of various diseases. However, most natural products have low solubility and …

How gallic acid regulates molecular signaling: role in cancer drug resistance

S Hassani, F Ghanbari, M Lotfi, W Alam, M Aschner… - Medical Oncology, 2023 - Springer
Cancer is one of the deadliest and most heterogeneous diseases. Cancers often develop
drug resistance, which can lead to treatment failure or recurrence. Accordingly, anticancer …

[HTML][HTML] Modulating inflammation-mediated diseases via natural phenolic compounds loaded in nanocarrier systems

TF Rakotondrabe, MX Fan, FW Muema, MQ Guo - Pharmaceutics, 2023 - mdpi.com
The global increase and prevalence of inflammatory-mediated diseases have been a great
menace to human welfare. Several works have demonstrated the anti-inflammatory …

[HTML][HTML] A multi-strategy platform for Q-markers screening and quality control of Wuzi Yanzong Wan based on fingerprint and network pharmacology

BH Dong, J Wu, Y Peng, YX Jiang, Y Huang… - Arabian Journal of …, 2024 - Elsevier
Abstract Wuzi Yanzong Wan (WZYZW) is a classic formula for tonifying the kidneys in
Traditional chinese medicine (TCM) and is widely used clinically in diseases of the …

Acetyl-terminated PAMAM dendrimers for pH-sensitive delivery of irinotecan and fluorouracil: A molecular dynamics simulation study

CY Hsu, AA Rajhi, E Ali, S Chandra, HH Ahmed… - Chemical Physics …, 2023 - Elsevier
Acetyl-terminated poly (amidoamine) dendrimer (G4ACE) was investigated as a pH-
responsive nanocarrier for co-delivery of irinotecan (IRI) and fluorouracil (FU) using …

Chebulinic acid inhibits MDA‐MB‐231 breast cancer metastasis and promotes cell death through down regulation of SOD1 and induction of autophagy

A Sharma, T Mishra, G Thacker, M Mishra… - Cell biology …, 2020 - Wiley Online Library
Triple‐negative breast cancers (TNBC) are highly aggressive and drug resistant accounting
for majority of cases with poor outcome. Purified natural compounds display substantial …

Nanoparticle-Delivered Gallic Acid: A New Frontier in Cancer Therapy

R Holghoomi, MH Kiani, A Rahdar, SM Hashemi… - Journal of Drug Delivery …, 2024 - Elsevier
Advances in targeted cancer therapy have been promoted by the integration of
nanotechnology and natural compounds. Gallic acid (GA), as a phenolic compound found in …