ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Good practices for 68Ga radiopharmaceutical production

BJB Nelson, JD Andersson, F Wuest… - EJNMMI …, 2022 - Springer
Abstract Background The radiometal gallium-68 (68Ga) is increasingly used in diagnostic
positron emission tomography (PET), with 68Ga-labeled radiopharmaceuticals developed …

Total body PET: why, how, what for?

S Surti, AR Pantel, JS Karp - IEEE transactions on radiation and …, 2020 - ieeexplore.ieee.org
PET instruments are now available with a long axial field-of-view (LAFOV) to enable imaging
the total-body, or at least head and torso, simultaneously and without bed translation. This …

Is prostate-specific membrane antigen positron emission tomography/computed tomography imaging cost-effective in prostate cancer: an analysis informed by the …

RE de Feria Cardet, MS Hofman, T Segard, J Yim… - European urology, 2021 - Elsevier
Background Before integrating prostate-specific membrane antigen (PSMA) positron
emission tomography/computed tomography (PET/CT) into routine care, it is important to …

The current status of the production and supply of gallium-68

K Kumar - Cancer biotherapy & radiopharmaceuticals, 2020 - liebertpub.com
Gallium-68 (68Ga) is an important radionuclide due to its successful use in the clinic.
Currently, 68Ga is produced and supplied by using germanium-68/Gallium-68 (68Ge/68Ga) …

Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) 18F-Radiopharmaceuticals

L Gower-Fry, T Kronemann, A Dorian, Y Pu… - Pharmaceuticals, 2021 - mdpi.com
The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules,
such as peptides, proteins and biologically relevant small molecules, has improved the …

Clinically applicable cyclotron-produced gallium-68 gives high-yield radiolabeling of DOTA-based tracers

E Jussing, S Milton, E Samén, MM Moein, L Bylund… - Biomolecules, 2021 - mdpi.com
By using solid targets in medical cyclotrons, it is possible to produce large amounts of
68GaCl3. Purification of Ga3+ from metal ion impurities is a critical step, as these metals …

[HTML][HTML] Demystifying solid targets: Simple and rapid distribution-scale production of [68Ga] GaCl3 and [68Ga] Ga-PSMA-11

J Svedjehed, M Pärnaste, K Gagnon - Nuclear Medicine and Biology, 2022 - Elsevier
Background As the demand for 68 Ga continues to grow, there is increasing interest in
single-to-multi-Curie production quantities of both [68 Ga] GaCl 3 and tracers such as [68 …

Analysis of Pros and Cons in Using [68Ga]Ga-PSMA-11 and [18F]PSMA-1007: Production, Costs, and PET/CT Applications in Patients with Prostate Cancer

C Maisto, M Aurilio, A Morisco, R de Marino… - Molecules, 2022 - mdpi.com
The aim of this work is to compare [68Ga] Ga-PSMA-11 and [18F] PSMA-1007 PET/CT as
imaging agents in patients with prostate cancer (PCa). Comparisons were made by …

Automated production of [18F] SiTATE on a Scintomics GRP™ platform for PET/CT imaging of neuroendocrine tumors

S Lindner, M Simmet, FJ Gildehaus, K Jurkschat… - Nuclear medicine and …, 2020 - Elsevier
Abstract Introduction [18 F] SiTATE (formerly known as [18 F] SiFAlin-TATE) was recently
introduced as a highly promising imaging agent for the diagnosis of well-differentiated …