Stimuli-responsive metal–organic framework nanoparticles for controlled drug delivery and medical applications

Z Zhou, M Vázquez-González, I Willner - Chemical Society Reviews, 2021 - pubs.rsc.org
Stimuli-responsive metal–organic framework nanoparticles, NMOFs, provide a versatile
platform for the controlled release of drugs and biomedical applications. The porous …

Switchable and dynamic G-quadruplexes and their applications

J Dong, MP O'Hagan, I Willner - Chemical Society Reviews, 2022 - pubs.rsc.org
G-Quadruplexes attract growing interest as functional constituents in biology, chemistry,
nanotechnology, and material science. In particular, the reversible dynamic reconfiguration …

[HTML][HTML] Artificial molecular machines

S Erbas-Cakmak, DA Leigh, CT McTernan… - Chemical …, 2015 - ACS Publications
The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Photoresponsive DNA materials and their applications

C Wang, MP O'Hagan, Z Li, J Zhang, X Ma… - Chemical Society …, 2022 - pubs.rsc.org
Photoresponsive nucleic acids attract growing interest as functional constituents in materials
science. Integration of photoisomerizable units into DNA strands provides an ideal handle …

Stimuli‐responsive nucleic acid‐based polyacrylamide hydrogel‐coated metal–organic framework nanoparticles for controlled drug release

WH Chen, WC Liao, YS Sohn, M Fadeev… - Advanced Functional …, 2018 - Wiley Online Library
The synthesis of doxorubicin‐loaded metal–organic framework nanoparticles (NMOFs)
coated with a stimuli‐responsive nucleic acid‐based polyacrylamide hydrogel is described …

[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures

F Wang, CH Lu, I Willner - Chemical reviews, 2014 - ACS Publications
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …

DNA switches: from principles to applications

F Wang, X Liu, I Willner - Angewandte Chemie International …, 2015 - Wiley Online Library
The base sequence of nucleic acid encodes structural and functional properties into the
biopolymer. Structural information includes the formation of duplexes, G‐quadruplexes, i …

i-Motif DNA: structure, stability and targeting with ligands

HA Day, P Pavlou, ZAE Waller - Bioorganic & medicinal chemistry, 2014 - Elsevier
Abstract i-Motifs are four-stranded DNA secondary structures which can form in sequences
rich in cytosine. Stabilised by acidic conditions, they are comprised of two parallel-stranded …

Highly ordered and field-free 3D DNA nanostructure: the next generation of DNA nanomachine for rapid single-step sensing

P Zhang, J Jiang, R Yuan, Y Zhuo… - Journal of the American …, 2018 - ACS Publications
Herein, by directly using Watson–Crick base pairing, a highly ordered and field-free three-
dimensional (3D) DNA nanostructure is self-assembled by azobenzene (azo)-functionalized …