Ghrelin induces adiposity in rodents
The discovery of the peptide hormone ghrelin, an endogenous ligand for the growth
hormone secretagogue (GHS) receptor,, yielded the surprising result that the principal site of …
hormone secretagogue (GHS) receptor,, yielded the surprising result that the principal site of …
The need to feed: homeostatic and hedonic control of eating
Feeding provides substrate for energy metabolism, which is vital to the survival of every
living animal and therefore is subject to intense regulation by brain homeostatic and hedonic …
living animal and therefore is subject to intense regulation by brain homeostatic and hedonic …
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …
releasing activity. This activity is mediated by the activation of the so-called GH …
Ghrelin-induced food intake is mediated via the orexin pathway
K Toshinai, Y Date, N Murakami, M Shimada… - …, 2003 - academic.oup.com
The hypothalamus regulates energy intake by integrating the degree of starvation or
satiation with the status of the environment through a variety of neuronal and blood-derived …
satiation with the status of the environment through a variety of neuronal and blood-derived …
Minireview: ghrelin and the regulation of energy balance—a hypothalamic perspective
The recently discovered hormone, ghrelin, has been recognized as an important regulator of
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by …
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by …
Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers
CB Lawrence, AC Snape, FMH Baudoin… - …, 2002 - academic.oup.com
Ghrelin was recently identified as the endogenous ligand for the GH secretagogue (GHS)
receptor. Like the synthetic GHSs [eg GH-releasing peptide-6 (GHRP-6)], ghrelin stimulates …
receptor. Like the synthetic GHSs [eg GH-releasing peptide-6 (GHRP-6)], ghrelin stimulates …
Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity
G Muccioli, M Tschöp, M Papotti, R Deghenghi… - European journal of …, 2002 - Elsevier
Ghrelin, a 28-amino acid acylated peptide predominantly produced by the stomach, displays
strong growth hormone (GH)-releasing activity mediated by the hypothalamus–pituitary GH …
strong growth hormone (GH)-releasing activity mediated by the hypothalamus–pituitary GH …
GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein
Ghrelin, an endogenous GH secretagogue, is capable of stimulating adiposity in rodents.
Because such adiposity was thought to be mediated by hypothalamic NPY neurons, we …
Because such adiposity was thought to be mediated by hypothalamic NPY neurons, we …
Repressor activity of Headless/Tcf3 is essential for vertebrate head formation
CH Kim, T Oda, M Itoh, DI Jiang, KB Artinger… - Nature, 2000 - nature.com
The vertebrate organizer can induce a complete body axis when transplanted to the ventral
side of a host embryo by virtue of its distinct head and trunk inducing properties …
side of a host embryo by virtue of its distinct head and trunk inducing properties …
Systemic administration of ghrelin induces Fos and Egr‐1 proteins in the hypothalamic arcuate nucleus of fasted and fed rats
AK Hewson, SL Dickson - Journal of neuroendocrinology, 2000 - Wiley Online Library
Ghrelin, a recently identified endogenous ligand for the growth hormone secretagogue
(GHS) receptor, induces growth hormone (GH) secretion following systemic administration …
(GHS) receptor, induces growth hormone (GH) secretion following systemic administration …