Targeting RNAs with small molecules represents a new frontier in drug discovery and
development. The rich structural diversity of folded RNAs offers a nearly unlimited reservoir …

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system
which is associated with numerous comorbidities. These include cardiovascular disease …

Neurodegeneration is the primary driver of disease progression in multiple sclerosis (MS)
resulting in permanent disability, creating an urgent need to discover its underlying …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central
nervous system (CNS). Small non-coding RNAs (sncRNAs) and, in particular, microRNAs …

Multiple sclerosis (MS) is an inflammatory brain disease with dysregulated expression of
over 8,800 genes and subnormal responses to type I interferon (IFN) by peripheral blood …

Alternative splicing (AS) is an important aspect of gene regulation. Nevertheless, its role in
molecular processes and pathobiology is far from understood. A roadblock is that tools for …

Background Multiple sclerosis (MS) is a chronic immune-mediated disease of the central
nervous system to which a genetic predisposition contributes. Over 200 genetic regions …

A pilot analysis of the tear fluid of patients with multiple sclerosis (MS) collected by glass
microcapillary was performed using various experimental methods: liquid chromatography …

Abstract Background Circular RNAs (circRNAs) are a class of non-coding RNAs increasingly
emerging as crucial actors in the pathogenesis of human diseases, including autoimmune …

Multiple sclerosis (MS) is a condition that is characterized by damage to the central nervous
system (CNS) that causes patients to experience cognitive and physical difficulties. Although …