A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives
K Chand, A Hiremathad, M Singh, MA Santos… - Pharmacological …, 2017 - Elsevier
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
Current progress on antioxidants incorporating the pyrazole core
VLM Silva, J Elguero, AMS Silva - European journal of medicinal chemistry, 2018 - Elsevier
The search of new antioxidants, as drugs candidates, is an active field of medicinal
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
Benzofuran derivatives: a patent review
KM Dawood - Expert opinion on therapeutic patents, 2013 - Taylor & Francis
Introduction: Benzofuran moiety constitutes the core of several interesting pharmacologically
active natural products. Benzofurans are among feasible potent active inhibitors against …
active natural products. Benzofurans are among feasible potent active inhibitors against …
Chalcones as Versatile Synthons for the Synthesis of 5-and 6-membered Nitrogen Heterocycles
H MT Albuquerque, C MM Santos… - Current Organic …, 2014 - ingentaconnect.com
Chalcones belong to the flavonoid family which constitutes one of the major classes of
naturally occurring oxygen heterocyclic compounds. The α, β-unsaturated carbonyl system …
naturally occurring oxygen heterocyclic compounds. The α, β-unsaturated carbonyl system …
New Hybrid Hydrazinyl Thiazole Substituted Chromones: As Potential α-Amylase Inhibitors and Radical (DPPH & ABTS) Scavengers
Current research is based on the identification of novel inhibitors of α-amylase enzyme. For
that purpose, new hybrid molecules of hydrazinyl thiazole substituted chromones 5–27 were …
that purpose, new hybrid molecules of hydrazinyl thiazole substituted chromones 5–27 were …
Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies
The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been
characterized and evaluated as potential anti-Alzheimer agents through in vitro …
characterized and evaluated as potential anti-Alzheimer agents through in vitro …
New hybrid scaffolds based on hydrazinyl thiazole substituted coumarin; as novel leads of dual potential; in vitro α-amylase inhibitory and antioxidant (DPPH and …
Background: Despite many side effects associated, there are many drugs which are being
clinically used for the treatment of type-II diabetes mellitus (DM). In this scenario, there is still …
clinically used for the treatment of type-II diabetes mellitus (DM). In this scenario, there is still …
4-Adamantyl-(2-(arylidene) hydrazinyl) thiazoles as potential antidiabetic agents: experimental and docking studies
Aim: To develop an efficient and cost-effective antidiabetic agent. Methods: A simple and
convenient Hantzsch synthetic strategy was used to prepare 4-adamantyl-(2-(arylidene) …
convenient Hantzsch synthetic strategy was used to prepare 4-adamantyl-(2-(arylidene) …
Synthesis of Thiazole‐Chalcone Hybrid Molecules: Antioxidant, Alpha (α)‐Amylase Inhibition and Docking Studies
The molecular hybrid approach is very significant to combat various drug‐resistant
disorders. A simple, convenient, and cost‐effective synthesis of thiazole‐based chalcones is …
disorders. A simple, convenient, and cost‐effective synthesis of thiazole‐based chalcones is …
Efficient one-pot synthesis of arylated pyrazole-fused pyran analogs: as leads to treating diabetes and Alzheimer's disease
Background: To discover novel lead molecules against diabetes, Alzheimer's disease and
oxidative stress, a library of arylated pyrazole-fused pyran derivatives, 1–20, were …
oxidative stress, a library of arylated pyrazole-fused pyran derivatives, 1–20, were …