BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …

Fibroblast growth factor 21 (FGF21) is a hormone that regulates important metabolic
pathways. FGF21 is expressed in several metabolically active organs and interacts with …

This prospective nonrandomized open-label cohort study addresses the safety and efficacy
of exosomes (ExoFlo™) derived from allogeneic bone marrow mesenchymal stem cells as …

Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …

Tissue regeneration by stem cells is driven by the paracrine activity of shedding vesicles and
exosomes, which deliver specific cargoes to the recipient cells. Proteins, RNA, cytokines and …

Red blood cells (RBCs) release extracellular vesicles (EVs) including both endosome-
derived exosomes and plasma-membrane-derived microvesicles (MVs). RBC-derived EVs …

An increasing number of studies have reported that exosomes released from various cells
can serve as mediators of information exchange between different cells. With further …

Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Recently, the emerging roles of adipocyte-derived extracellular vesicles (EVs) linking
obesity and its comorbidities have been recognized. In obese subjects, adipocytes are …