Haptoglobin: From hemoglobin scavenging to human health

A di Masi, G De Simone, C Ciaccio, S D'Orso… - Molecular Aspects of …, 2020 - Elsevier
Haptoglobin (Hp) belongs to the family of acute-phase plasma proteins and represents the
most important plasma detoxifier of hemoglobin (Hb). The basic Hp molecule is a tetrameric …

Circulating proteins as diagnostic markers in gastric cancer

O Repetto, R Vettori, A Steffan, R Cannizzaro… - International Journal of …, 2023 - mdpi.com
Gastric cancer (GC) is a highly malignant disease affecting humans worldwide and has a
poor prognosis. Most GC cases are detected at advanced stages due to the cancer lacking …

Metabolomics identifies serum and exosomes metabolite markers of pancreatic cancer

L Tao, J Zhou, C Yuan, L Zhang, D Li, D Si, D Xiu… - Metabolomics, 2019 - Springer
Introduction Pancreatic cancer (PC) is one of the most aggressive malignancies, and it's
difficult to diagnosis PC at an early stage, which leads to the poor prognosis of PC …

Blood-based liquid biopsy: Insights into early detection, prediction, and treatment monitoring of bladder cancer

S Li, K Xin, S Pan, Y Wang, J Zheng, Z Li, X Liu… - Cellular & Molecular …, 2023 - Springer
Bladder cancer (BC) is a clinical challenge worldwide with late clinical presentation, poor
prognosis, and low survival rates. Traditional cystoscopy and tissue biopsy are routine …

Haptoglobin as a Biomarker

SN Naryzny, OK Legina - Biochemistry (Moscow), Supplement Series B …, 2021 - Springer
Haptoglobin (Hp) is a glycoprotein that binds free hemoglobin (Hb) in plasma and plays a
critical role in tissue protection and prevention of oxidative damage. Besides, it has some …

Comprehensive serum glycopeptide spectra analysis to identify early-stage epithelial ovarian cancer

M Mikami, K Tanabe, T Imanishi, M Ikeda… - Scientific Reports, 2024 - nature.com
Epithelial ovarian cancer (EOC) is widely recognized as the most lethal gynecological
malignancy; however, its early-stage detection remains a considerable clinical challenge. To …

Glycopeptide biomarkers in serum haptoglobin for hepatocellular carcinoma detection in patients with nonalcoholic steatohepatitis

J Zhu, J Huang, J Zhang, Z Chen, Y Lin… - Journal of proteome …, 2020 - ACS Publications
Nonalcoholic steatohepatitis (NASH) is rising in prevalence in the United States and is a
growing cause of hepatocellular carcinomas (HCCs). Site-specific glycan heterogeneity on …

Recent liquid chromatographic approaches and developments for the separation and purification of carbohydrates

G Nagy, T Peng, NLB Pohl - Analytical Methods, 2017 - pubs.rsc.org
Carbohydrate purification remains a bottleneck in securing analytical standards from natural
sources or by chemical or enzymatic synthesis. This review highlights the scope and …

Therapy-induced senescent cancer cells contribute to cancer progression by promoting ribophorin 1-dependent PD-L1 upregulation

HJ Hwang, D Kang, J Shin, J Jung, S Ko… - Nature …, 2025 - nature.com
Conventional chemotherapy-and radiotherapy-induced cancer senescence, which is
characterized by poor proliferation, drug resistance, and senescence-associated secretory …

Haptoglobin as a biomarker

SN Naryzhny, OK Legina - Biomeditsinskaya khimiya, 2021 - pbmc.ibmc.msk.ru
Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays
a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a …