Therapeutic potential of certain terpenoids as anticancer agents: a scoping review

S Kamran, A Sinniah, MAM Abdulghani, MA Alshawsh - Cancers, 2022 - mdpi.com
Simple Summary Terpenoids are bioactive compounds with a variety of pharmacological
activities, including anticancer activity. This review paper aimed to focus on the anticancer …

Cancer models in preclinical research: A chronicle review of advancement in effective cancer research

H Sajjad, S Imtiaz, T Noor, YH Siddiqui… - Animal Models and …, 2021 - Wiley Online Library
Cancer is a major stress for public well‐being and is the most dreadful disease. The models
used in the discovery of cancer treatment are continuously changing and extending toward …

DeepSynergy: predicting anti-cancer drug synergy with Deep Learning

K Preuer, RPI Lewis, S Hochreiter, A Bender… - …, 2018 - academic.oup.com
Motivation While drug combination therapies are a well-established concept in cancer
treatment, identifying novel synergistic combinations is challenging due to the size of …

DeepDDS: deep graph neural network with attention mechanism to predict synergistic drug combinations

J Wang, X Liu, S Shen, L Deng… - Briefings in …, 2022 - academic.oup.com
Motivation Drug combination therapy has become an increasingly promising method in the
treatment of cancer. However, the number of possible drug combinations is so huge that it is …

AMP kinase promotes glioblastoma bioenergetics and tumour growth

RR Chhipa, Q Fan, J Anderson, R Muraleedharan… - Nature cell …, 2018 - nature.com
Stress is integral to tumour evolution, and cancer cell survival depends on stress
management. We found that cancer-associated stress chronically activates the bioenergetic …

Cancer drug development: The missing links

AB Kunnumakkara, D Bordoloi… - Experimental …, 2019 - journals.sagepub.com
Although better science and technology has been linked with better health care, however,
reality is much different. Although America and most of Europe are equipped with most …

Breast cancer in sub-Saharan Africa: The current state and uncertain future

CA Anyigba, GA Awandare… - … Biology and Medicine, 2021 - journals.sagepub.com
Breast cancer is the commonest cause of global cancer-related deaths in women and a
public health burden in sub-Saharan Africa (SSA). Although the disease incidence in SSA …

History of cell culture

M Jedrzejczak-Silicka - New insights into cell culture technology, 2017 - books.google.com
From the ancient Romans, through the Middle Ages, to the late of the nineteenth century, the
Aristotelian doctrine of spontaneous generation was one of the most basic laws. Even the …

DFFNDDS: prediction of synergistic drug combinations with dual feature fusion networks

M Xu, X Zhao, J Wang, W Feng, N Wen, C Wang… - Journal of …, 2023 - Springer
Drug combination therapies are promising clinical treatments for curing patients. However,
efficiently identifying valid drug combinations remains challenging because the number of …

N-glycosylation profiling of colorectal cancer cell lines reveals association of fucosylation with differentiation and caudal type homebox 1 (CDX1)/Villin mRNA …

S Holst, AJM Deuss, GW Van Pelt, SJ Van Vliet… - Molecular & Cellular …, 2016 - ASBMB
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein
glycosylation. CRC cell lines are frequently used to study these (glyco) biological changes …