Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …

Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Anabolic–androgenic steroids (AAS) are a class of hormones that are widely abused for
their muscle-building and strength-increasing properties in high, nontherapeutic, dosages …

Genes underneath signals from genome-wide association studies (GWAS) for kidney
function are promising targets for functional studies, but prioritizing variants and genes is …

Chronic kidney disease (CKD) is currently defined by abnormalities of kidney structure or
function assessed using a matrix of variables—including glomerular filtration rate (GFR) …

New biomarkers are being evaluated for their ability to advance the management of patients
with heart failure. Despite a large pool of interesting candidate biomarkers, besides …

In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

Background Estimates of glomerular filtration rate (GFR) that are based on serum creatinine
are routinely used; however, they are imprecise, potentially leading to the overdiagnosis of …

Background Adding the measurement of cystatin C to that of serum creatinine to determine
the estimated glomerular filtration rate (eGFR) improves accuracy, but the effect on …

Assessment of GFR is central to clinical practice, research, and public health. Current
Kidney Disease Improving Global Outcomes guidelines recommend measurement of serum …