[HTML][HTML] Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications
B Deslouches, YP Di - Oncotarget, 2017 - ncbi.nlm.nih.gov
In the last several decades, there have been significant advances in anticancer therapy.
However, the development of resistance to cancer drugs and the lack of specificity related to …
However, the development of resistance to cancer drugs and the lack of specificity related to …
Acellular and cellular approaches to improve diabetic wound healing
Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …
individuals and the entire healthcare system. Although the number of available treatment …
Membrane active peptides and their biophysical characterization
In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …
active peptides. These peptides exert their biological activity by interacting with the cell …
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens
Antimicrobial peptides (AMPs) are promising next-generation antibiotics that can be used to
combat drug-resistant pathogens. However, the high cost involved in AMP synthesis and …
combat drug-resistant pathogens. However, the high cost involved in AMP synthesis and …
Enhanced therapeutic index of an antimicrobial peptide in mice by increasing safety and activity against multidrug-resistant bacteria
The rising prevalence of antibiotic resistance underscores the urgent need for novel
antimicrobial agents. Antimicrobial peptides (AMPs) are potentially effective therapeutics …
antimicrobial agents. Antimicrobial peptides (AMPs) are potentially effective therapeutics …
Association of idealized amphiphiles and protease inhibitors: Conferring antimicrobial peptides with stable antibacterial activity under physiological conditions to …
Y Zhu, B Li, W Xu, Y Wang, G Li, C Bi, A Shan… - Drug Resistance …, 2025 - Elsevier
Aims The unstable antimicrobial activity of antimicrobial peptides (AMPs) under
physiological conditions (especially the degradation instigated proteases) seems to be a …
physiological conditions (especially the degradation instigated proteases) seems to be a …
Improving the activity of Trp-rich antimicrobial peptides by Arg/Lys substitutions and changing the length of cationic residues
Antimicrobial peptides (AMPs) constitute a promising alternative for the development of new
antibiotics that could potentially counteract the growing number of antibiotic-resistant …
antibiotics that could potentially counteract the growing number of antibiotic-resistant …
Selectivity of antimicrobial peptides: a complex interplay of multiple equilibria
S Bobone, L Stella - Antimicrobial Peptides: Basics for Clinical Application, 2019 - Springer
Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …
Antifungal and Antibiofilm Activities and the Mechanism of Action of Repeating Lysine-Tryptophan Peptides against Candida albicans
G Ramamourthy, J Park, C Seo, H J. Vogel, Y Park - Microorganisms, 2020 - mdpi.com
The rapid increase in the emergence of antifungal-resistant Candida albicans strains is
becoming a serious health concern. Because antimicrobial peptides (AMPs) may provide a …
becoming a serious health concern. Because antimicrobial peptides (AMPs) may provide a …
Engineered cationic antimicrobial peptides (eCAPs) to combat multidrug-resistant bacteria
B Deslouches, RC Montelaro, KL Urish, YP Di - Pharmaceutics, 2020 - mdpi.com
The increasing rate of antibiotic resistance constitutes a global health crisis. Antimicrobial
peptides (AMPs) have the property to selectively kill bacteria regardless of resistance to …
peptides (AMPs) have the property to selectively kill bacteria regardless of resistance to …