Chikungunya fever

K Bartholomeeusen, M Daniel, DA LaBeaud… - Nature Reviews …, 2023 - nature.com
Chikungunya virus is widespread throughout the tropics, where it causes recurrent
outbreaks of chikungunya fever. In recent years, outbreaks have afflicted populations in East …

Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies

LA Silva, TS Dermody - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …

Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy

SD Thiberville, N Moyen, L Dupuis-Maguiraga… - Antiviral research, 2013 - Elsevier
Chikungunya virus (CHIKV) is the aetiological agent of the mosquito-borne disease
chikungunya fever, a debilitating arthritic disease that, during the past 7 years, has caused …

Animal models in biological and biomedical research-experimental and ethical concerns

ML Andersen, LMF Winter - Anais da Academia Brasileira de Ciências, 2017 - SciELO Brasil
Animal models have been used in experimental research to increase human knowledge
and contribute to finding solutions to biological and biomedical questions. However …

Chikungunya: a re-emerging virus

FJ Burt, MS Rolph, NE Rulli, S Mahalingam, MT Heise - The Lancet, 2012 - thelancet.com
In the past decade, chikungunya—a virus transmitted by Aedes spp mosquitoes—has re-
emerged in Africa, southern and southeastern Asia, and the Indian Ocean Islands as the …

Rheumatic manifestations of chikungunya: emerging concepts and interventions

A Suhrbier - Nature Reviews Rheumatology, 2019 - nature.com
The largest epidemic ever recorded for chikungunya, a disease caused by infection with the
chikungunya virus (CHIKV), began in Africa in 2004 and spread to> 100 countries on four …

Arthritogenic alphaviruses—an overview

A Suhrbier, MC Jaffar-Bandjee, P Gasque - Nature Reviews …, 2012 - nature.com
Mosquito-transmitted alphaviruses causing human rheumatic disease are globally
distributed and include chikungunya virus, Ross River virus, Barmah Forest virus, Sindbis …

A single mutation in chikungunya virus affects vector specificity and epidemic potential

KA Tsetsarkin, DL Vanlandingham, CE McGee… - PLoS …, 2007 - journals.plos.org
Chikungunya virus (CHIKV) is an emerging arbovirus associated with several recent large-
scale epidemics. The 2005–2006 epidemic on Reunion island that resulted in approximately …

Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response

JJ Hoarau, MC Jaffar Bandjee… - The Journal of …, 2010 - journals.aai.org
Alphaviruses, including Chikungunya virus (CHIKV), produce a transient illness in humans,
but severe forms leading to chronic incapacitating arthralgia/arthritis have been reported by …

Biology and pathogenesis of chikungunya virus

O Schwartz, ML Albert - Nature Reviews Microbiology, 2010 - nature.com
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus responsible for a
recent, unexpectedly severe epidemic in countries of the Indian Ocean region. Although …