Deletions in mitochondrial DNA (mtDNA) are associated with diverse human pathologies
including cancer, aging and mitochondrial disorders. Large-scale deletions span kilobases …

In human cells, nucleic acids adopt several non-canonical structures that regulate key
cellular processes. Among them, G-quadruplexes (G4s) are stable structures that form in …

Mitochondria are specialized compartments that produce requisite ATP to fuel cellular
functions and serve as centers of metabolite processing, cellular signaling, and apoptosis …

Mitochondria participate in a wide range of cellular processes. One essential function of
mitochondria is to be a platform for antiviral signaling proteins during the innate immune …

The excessive production of reactive oxygen species (ROS) can lead to single nucleic acid
base damage, DNA strand breakage, inter-and intra-strand cross-linking of nucleic acids …

The selective monitoring of G‐quadruplex (G4) structures in living cells is important to
elucidate their functions and reveal their value as diagnostic or therapeutic targets. Here we …

Biomolecular polyelectrolyte complexes can be formed between oppositely charged
intrinsically disordered regions (IDRs) of proteins or between IDRs and nucleic acids. Highly …

A first example of a mitochondrial G‐quadruplex (mitoG4s) targeted Ru (II) photooxidant
complex is reported. The complex, Ru‐TAP‐PDC3 induces photodamage toward guanine …

The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …

Single-stranded DNA or RNA sequences rich in guanine (G) can adopt non-canonical
structures known as G-quadruplexes (G4). Mitochondrial DNA (mtDNA) sequences that are …