EMT transition states during tumor progression and metastasis

I Pastushenko, C Blanpain - Trends in cell biology, 2019 - cell.com
Epithelial–mesenchymal transition (EMT) is a process in which epithelial cells acquire
mesenchymal features. In cancer, EMT is associated with tumor initiation, invasion …

NF-κB addiction and its role in cancer:'one size does not fit all'

MM Chaturvedi, B Sung, VR Yadav, R Kannappan… - Oncogene, 2011 - nature.com
Activation of nuclear factor (NF)-κB, one of the most investigated transcription factors, has
been found to control multiple cellular processes in cancer including inflammation …

Redox regulation in cancer: a double‐edged sword with therapeutic potential

A Acharya, I Das, D Chandhok… - Oxidative medicine and …, 2010 - Wiley Online Library
Oxidative stress, implicated in the etiology of cancer, results from an imbalance in the
production of reactive oxygen species (ROS) and cell's own antioxidant defenses. ROS …

Cell-type-specific chromatin states differentially prime squamous cell carcinoma tumor-initiating cells for epithelial to mesenchymal transition

M Latil, D Nassar, B Beck, S Boumahdi, L Wang… - Cell stem cell, 2017 - cell.com
Epithelial to mesenchymal transition (EMT) in cancer cells has been associated with
metastasis, stemness, and resistance to therapy. Some tumors undergo EMT while others do …

Identification of endometrioid endometrial carcinoma-associated microRNAs in tissue and plasma

O Tsukamoto, K Miura, H Mishima, S Abe… - Gynecologic …, 2014 - Elsevier
Objective This study aimed to identify a set of endometrioid endometrial carcinoma EEC-
associated microRNAs (miRNAs) in tissue and plasma, and evaluate their clinical …

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation

W Dong, Y Li, M Gao, M Hu, X Li, S Mai… - Nucleic acids …, 2012 - academic.oup.com
Exposure to ultraviolet B (UVB) irradiation from sunlight induces the upregulation of VEGF, a
potent angiogenic factor that is critical for mediating angiogenesis-associated photodamage …

The role of barrier genes in epidermal malignancy

C Darido, SR Georgy, SM Jane - Oncogene, 2016 - nature.com
The outermost layer of the mammalian skin, the epidermis, forms a protective barrier against
pathogenic microbes and tissue dehydration. This barrier is formed and maintained by …

Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus

H Chen, J Li, H Li, Y Hu, W Tevebaugh, M Yamamoto… - PloS one, 2012 - journals.plos.org
Background and Aims Morphological changes during human and mouse esophageal
development have been well characterized. However, changes at the molecular level in the …

Deep-Sequencing Analysis of the Mouse Transcriptome Response to Infection with Brucella melitensis Strains of Differing Virulence

F Wang, S Hu, W Liu, Z Qiao, Y Gao, Z Bu - PloS one, 2011 - journals.plos.org
Brucella melitensis is an important zoonotic pathogen that causes brucellosis, a disease that
affects sheep, cattle and occasionally humans. B. melitensis strain M5-90, a live attenuated …

NF-κB signalling is attenuated by the E7 protein from cutaneous human papillomaviruses

LM Byg, J Vidlund, N Vasiljevic, D Clausen, O Forslund… - Virus research, 2012 - Elsevier
The high-risk Alpha-types of human papillomavirus (HPV) are the causative agent of cervical
cancer, which is the second major cause of death among women worldwide. Recent …