The role of microRNAs in glucocorticoid action

SA Clayton, SW Jones, M Kurowska-Stolarska… - Journal of Biological …, 2018 - ASBMB
Glucocorticoids (GCs) are steroids with profound anti-inflammatory and immunomodulatory
activities. Synthetic GCs are widely used for managing chronic inflammatory and …

MicroRNAs as a potential new preventive approach in the transition from asymptomatic to symptomatic multiple myeloma disease

V Desantis, AG Solimando, I Saltarella, A Sacco… - Cancers, 2021 - mdpi.com
Simple Summary Multiple myeloma (MM) is the second most common haematologic
malignancy, and it remains an incurable disease despite the advances of novel therapies. It …

High-throughput sequencing of microRNAs in glucocorticoid sensitive paediatric inflammatory bowel disease patients

S De Iudicibus, M Lucafò, N Vitulo, S Martelossi… - International Journal of …, 2018 - mdpi.com
The aim of this research was the identification of novel pharmacogenomic biomarkers for
better understanding the complex gene regulation mechanisms underpinning glucocorticoid …

Covalent cysteine targeting of bruton's tyrosine kinase (BTK) family by Withaferin-A reduces survival of glucocorticoid-resistant multiple myeloma mm1 cells

E Logie, CS Chirumamilla, C Perez-Novo, P Shaw… - Cancers, 2021 - mdpi.com
Simple Summary Glucocorticoid therapy resistance in B-cell malignancies is often
associated with constitutive activation of tyrosine kinases. Novel anticancer drugs targeting …

Phosphocatalytic kinome activity profiling of apoptotic and ferroptotic agents in multiple myeloma cells

E Logie, CP Novo, A Driesen… - International journal of …, 2021 - mdpi.com
Through phosphorylation of their substrate proteins, protein kinases are crucial for
transducing cellular signals and orchestrating biological processes, including cell death and …

[PDF][PDF] Covalent Cysteine Targeting of Bruton Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid Resistant Multiple Myeloma MM1 Cells …

E Logie, CS Chirumamilla, C Perez-Novo, P Shaw… - 2021 - medialibrary.uantwerpen.be
Multiple myeloma (MM) is a hematological malignancy characterized by plasma cells'
uncontrolled growth. The major barrier in treating MM is the occurrence of primary and …

Identification of molecular targets in the pathogenesis of multiple myeloma/Ivyna Bong Pau Ni

BPN Ivyna - 2017 - studentsrepo.um.edu.my
Multiple myeloma (MM) is a cancer of plasma cells. It is a highly heterogenous disease
composed of numerous molecularly defined subtypes, each with varying clinicopathological …

Identification of Molecular Targets in the Pathogenesis of Multiple Myeloma

IBP Ni - 2017 - search.proquest.com
Multiple myeloma (MM) is a cancer of plasma cells. It is a highly heterogenous disease
composed of numerous molecularly defined subtypes, each with varying clinicopathological …