▪ Abstract The secretion of fluid and electrolytes by salivary gland acinar cells requires the
coordinated regulation of multiple water and ion transporter and channel proteins. Notably …

Darier disease (DD) is a type of inherited keratinizing disorder that exhibits autosomal
dominant inheritance. DD is caused by the mutations of ATP 2A2, which encodes an …

Store-operated calcium entry (SOCE) is a ubiquitous mechanism that is mediated by distinct
SOC channels, ranging from the highly selective calcium release-activated Ca 2+(CRAC) …

Trp1 has been proposed as a component of the store-operated Ca 2+ entry (SOC) channel.
However, neither the molecular mechanism of SOC nor the role of Trp in this process is yet …

Homologues of Drosophila Trp (transient receptor potential) form plasma membrane
channels that mediate Ca 2+ entry following the activation of phospholipase C by cell …

The trp gene family has been proposed to encode the store-operated Ca 2+ influx (SOC)
channel (s). This study examines the role of Trp1 in the SOC mechanism of salivary gland …

Mammalian homologues of Drosophila Trp form plasma membrane channels that mediate
Ca2+ influx in response to activation of phospholipase C and internal Ca2+ store depletion …

The exact role of TRPC1 in store-operated calcium influx channel (SOCC) function is not
known. We have examined the effect of overexpression of full-length TRPC1, depletion of …

The TRPC1 (transient receptor potential canonical-1) channel is a constituent of the
nonselective cation channel that mediates Ca 2+ entry through store-operated channels …

The mechanism involved in [Ca 2+] i-dependent feedback inhibition of store-operated Ca 2+
entry (SOCE) is not yet known. Expression of Ca 2+-insensitive calmodulin (Mut-CaM) but …