Effect of environmental air pollutants on placental function and pregnancy outcomes: A molecular insight

S Singh, I Goel, S Tripathi, A Ahirwar, M Kumar… - … Science and Pollution …, 2024 - Springer
Air pollution has become a major health concern, particularly for vulnerable populations
such as the elderly, children, and pregnant women. Studies have reported a strong …

Impact of endocrine disrupting chemicals and pharmaceuticals on Sertoli cell development and functions

M Corpuz-Hilsabeck, M Culty - Frontiers in Endocrinology, 2023 - frontiersin.org
Sertoli cells play essential roles in male reproduction, from supporting fetal testis
development to nurturing male germ cells from fetal life to adulthood. Dysregulating Sertoli …

[HTML][HTML] Maternal phthalate exposure during pregnancy and testis function of young adult sons

LS Henriksen, H Frederiksen, N Jørgensen… - Science of the Total …, 2023 - Elsevier
Background Phthalate exposure during fetal life may disrupt testicular development.
Congruent with this, studies have found shorter anogenital distance, reduced penile size …

The role of small GTPases in bisphenol AF-induced multinucleation in comparison with dibutyl phthalate in the male germ cells

C Hu, ZH Hsiao, L Yin, X Yu - Toxicological Sciences, 2023 - academic.oup.com
The goal of this study is to examine bisphenol AF (BPAF)-induced multinucleation (MNC) in
comparison with dibutyl phthalate (DBP), known to induce MNC in mouse gonocytes in vivo …

Impact of fetal exposure to endocrine disrupting chemical mixtures on FOXA3 gene and protein expression in adult rat testes

C Walker, A Boisvert, P Malusare, M Culty - International journal of …, 2023 - mdpi.com
Perinatal exposure to endocrine disrupting chemicals (EDCs) has been shown to affect male
reproductive functions. However, the effects on male reproduction of exposure to EDC …

Mechanisms of MEHP inhibitory action and analysis of potential replacement plasticizers on Leydig cell steroidogenesis

AN Enangue Njembele, JJ Tremblay - International Journal of Molecular …, 2021 - mdpi.com
Steroid production in Leydig cells is stimulated mainly by the pituitary luteinizing hormone,
which leads to increased expression of genes involved in steroidogenesis, including the …

[HTML][HTML] An in vitro testicular organoid model for the study of testis morphogenesis, somatic cell maturation, endocrine function, and toxicological assessment of …

TC Cham, F Ibtisham, A Al-Dissi, A Honaramooz - Reproductive Toxicology, 2024 - Elsevier
Male reproductive capacity has fallen considerably in recent decades; in addition, the
incidence of testicular cancer has increased in many developed countries. The cause of this …

The mechanism of monobutyl phthalate-induced ferroptosis via TNF/IL6/STAT3 signal pathway in TM-3 cells

X Guo, Y Hao, H Ma, H Li, L Li, F Yan… - The Journal of …, 2023 - jstage.jst.go.jp
As a common environmental endocrine disruptor, monobutyl phthalate (MBP) has been
connected to reports of ROS accumulation, sperm destruction and reproductive damage …

[HTML][HTML] Is There a Relationship Between Prenatal Dexamethasone and Postnatal Fructose Overexposure and Testicular Development, Function, and Oxidative Stress …

N Ristić, S Borković-Mitić… - International Journal of …, 2024 - mdpi.com
Prenatal glucocorticoid overexposure alters the developmental program of fetal reproductive
organs and results in numerous changes that can lead to various disorders later in life …

[HTML][HTML] Analysis of Plasticizer Contamination Throughout Olive Oil Production

F Freitas, J Brinco, MJ Cabrita, M Gomes da Silva - Molecules, 2024 - mdpi.com
This study monitored the contamination of 32 plasticizers in olive oil throughout the
production and storage process. Samples were collected at different stages of production …