Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The
pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved …

Background Platelet count alone does not reliably predict bleeding risk, suggesting platelet
function is important to monitor in patients with thrombocytopenia. There is still an unmet …

During the past decades, it has been increasingly recognized that the major function of
accelerating membrane-dependent reactions of blood coagulation is predominantly …

Thrombopoietin receptor agonist (TPO-RA) treatment increases the thrombosis rate in
immune thrombocytopenia (ITP). We hypothesize that TPO-RAs influence platelet function …

The hematological effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) are important in COVID-19 pathophysiology. However, the interactions of SARS-CoV-2 …

Immune thrombocytopenia (ITP) is believed to be associated with platelet function defects.
However, their mechanisms are poorly understood, in particular with regard to differences …

Immune thrombocytopenia (ITP) is an autoimmune condition primarily induced by the loss of
immune tolerance to the platelet glycoproteins. Here we develop a novel flow cytometry …

Thrombopoietin receptor agonists (TPO‐RAs) stimulate platelet production, which might
restore immunological tolerance in primary immune thrombocytopenia (ITP). The iROM …

Background Patients with primary immune thrombocytopenia (ITP) have an increased risk of
thrombosis, which may be due to altered fibrinolysis. Objectives To elucidate the clinical …

No biological predictors for the increased risk of thrombosis in patients with immune
thrombocytopenia (ITP) have been identified. The aim of the study was to investigate platelet …