Alzheimer's disease (AD) is an irreversible neurological disorder that progresses gradually
and can cause severe cognitive and behavioral impairments. This disease is currently …

Alzheimer's disease (AD) is the fifth leading cause of death on the planet. It hallmarks the
presence of amyloid plaques and neurofibrillary tangles in geriatric patients. The condition …

Excessive accumulations of reactive oxygen species (ROS) and amyloid‐β (Aβ) protein are
closely associated with the complex pathogenesis of Alzheimer's disease (AD). Therefore …

Charge transfer plays a key role in the structural transformation of amyloid-β proteins (Aβs),
as it fibrillizes from small monomers to intermediate oligomers and to ordered fibrils. While …

Early detection of peptide aggregate intermediates is quite challenging because of their
variable and complex nature as well as due to lack of reliable sensors for diagnosis. Herein …

Amyloid fibrils generally display chirality, a feature which has rarely been exploited in the
development of therapeutics against amyloid diseases. This study reports, for the first time …

Peptidic nanodiscs are useful membrane mimetic tools for structural and functional studies
of membrane proteins, and membrane interacting peptides including amyloids. Here, we …

Amyloid-β [Aβ (1–40)] aggregation into a fibrillar network is one of the major hallmarks of
Alzheimer's disease (AD). Recently, a few studies reported that polyphosphate (polyP), an …

The generation of highly organized amyloid fibrils is associated with a wide range of
conformational pathologies, including primarily neurodegenerative diseases. Such …

Amyloid β-protein (Aβ) aggregation is crucial for the pathogenesis of Alzheimer's disease,
and surface charge of nanoparticles (NPs) has been recognized as an important factor …