A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions
Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …
A review on drug repurposing applicable to COVID-19
S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …
cost and in a shorter time. There are different computational drug-repurposing strategies and …
Drug repositioning based on the heterogeneous information fusion graph convolutional network
In silico reuse of old drugs (also known as drug repositioning) to treat common and rare
diseases is increasingly becoming an attractive proposition because it involves the use of de …
diseases is increasingly becoming an attractive proposition because it involves the use of de …
Drug repurposing from the perspective of pharmaceutical companies
Drug repurposing holds the potential to bring medications with known safety profiles to new
patient populations. Numerous examples exist for the identification of new indications for …
patient populations. Numerous examples exist for the identification of new indications for …
[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …
A survey of current trends in computational drug repositioning
Computational drug repositioning or repurposing is a promising and efficient tool for
discovering new uses from existing drugs and holds the great potential for precision …
discovering new uses from existing drugs and holds the great potential for precision …
A review of network-based approaches to drug repositioning
M Lotfi Shahreza, N Ghadiri, SR Mousavi… - Briefings in …, 2018 - academic.oup.com
Experimental drug development is time-consuming, expensive and limited to a relatively
small number of targets. However, recent studies show that repositioning of existing drugs …
small number of targets. However, recent studies show that repositioning of existing drugs …
Role of traditional Chinese medicine in bone regeneration and osteoporosis
Z Peng, R Xu, Q You - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
According to World Health Organization (WHO), osteoporosis is a systematic bone disability
marked by reduced bone mass and microarchitectural degeneration of osseous cells, which …
marked by reduced bone mass and microarchitectural degeneration of osseous cells, which …
In silico methods for drug repurposing and pharmacology
Data in the biological, chemical, and clinical domains are accumulating at ever‐increasing
rates and have the potential to accelerate and inform drug development in new ways …
rates and have the potential to accelerate and inform drug development in new ways …
SperoPredictor: an integrated machine learning and molecular docking-based drug repurposing framework with use case of COVID-19
F Ahmed, JW Lee, A Samantasinghar, YS Kim… - Frontiers in public …, 2022 - frontiersin.org
The global spread of the SARS coronavirus 2 (SARS-CoV-2), its manifestation in human
hosts as a contagious disease, and its variants have induced a pandemic resulting in the …
hosts as a contagious disease, and its variants have induced a pandemic resulting in the …