Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations

GK Bertsias, DT Boumpas - Nature Reviews Rheumatology, 2010 - nature.com
Neuropsychiatric events are common in patients with systemic lupus erythematosus (SLE),
but less than one-third of these events can be directly attributed to SLE. Increased …

The diagnosis and clinical management of the neuropsychiatric manifestations of lupus

M Govoni, A Bortoluzzi, M Padovan, E Silvagni… - Journal of …, 2016 - Elsevier
Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

Cerebrovascular disease in rheumatic diseases: a systematic review and meta-analysis

SJ Wiseman, SH Ralston, JM Wardlaw - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Some rheumatic diseases are associated with stroke. Less is
known about associations with stroke subtypes or stroke risk by age. We quantified the …

Brain abnormalities in newly diagnosed neuropsychiatric lupus: systematic MRI approach and correlation with clinical and laboratory data in a large multicenter cohort

N Sarbu, F Alobeidi, P Toledano, G Espinosa, I Giles… - Autoimmunity …, 2015 - Elsevier
Objectives To describe brain magnetic resonance imaging (MRI) abnormalities in newly
diagnosed neuropsychiatric lupus (NPSLE). To correlate them with clinical and laboratory …

What is the prevalence of cognitive impairment in lupus and which instruments are used to measure it? A systematic review and meta-analysis

H Al Rayes, C Tani, A Kwan, S Marzouk… - Seminars in arthritis and …, 2018 - Elsevier
Objectives To systematically review the literature on the prevalence of Cognitive Dysfunction
(CD) in SLE patients in studies that used a specified neuropsychological instrument …

From systemic inflammation to neuroinflammation: the case of neurolupus

M Bendorius, C Po, S Muller… - International journal of …, 2018 - mdpi.com
It took decades to arrive at the general consensus dismissing the notion that the immune
system is independent of the central nervous system. In the case of uncontrolled systemic …

Structural changes of the brain in rheumatoid arthritis

K Wartolowska, MG Hough, M Jenkinson… - Arthritis & …, 2012 - Wiley Online Library
Objective To investigate whether structural changes are present in the cortical and
subcortical gray matter of the brains of patients with rheumatoid arthritis (RA). Methods We …

Neuropsychiatric systemic lupus erythematosus: magnetic resonance imaging findings and correlation with clinical and immunological features

P Toledano, N Sarbu, G Espinosa, N Bargalló… - Autoimmunity …, 2013 - Elsevier
Neuropsychiatric (NP) syndromes are a major cause of morbidity and mortality in patients
with systemic lupus erythematosus (SLE). The aims of this work were to describe the brain …

Magnetic resonance imaging in neuropsychiatric systemic lupus erythematosus: current state of the art and novel approaches

M Postal, AT Lapa, F Reis, L Rittner, S Appenzeller - Lupus, 2017 - journals.sagepub.com
Systemic lupus erythematosus is a chronic, inflammatory, immune-mediated disease
affecting 0.1% of the general population. Neuropsychiatric manifestations in systemic lupus …

Cerebral small vessel disease burden is increased in systemic lupus erythematosus

SJ Wiseman, ME Bastin, CL Jardine, G Barclay… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Systemic lupus erythematosus (SLE) increases stroke risk, but
the mechanism is uncertain. This study aimed to determine the association between SLE …