An effective peptide-based platform for efficient exosomal loading and cellular delivery of a microRNA

MD Hade, CN Suire, Z Suo - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Exosomes, membrane-bound nanosized vesicles of biologic origin, are known to contain
various molecules, eg, proteins, lipids, and nucleic acids, which contribute to the exosomes' …

Significant enhancement of fibroblast migration, invasion, and proliferation by exosomes loaded with human fibroblast growth factor 1

MD Hade, CN Suire, Z Suo - ACS Applied Materials & Interfaces, 2024 - ACS Publications
Exosomes possess several inherent properties that make them ideal for biomedical
applications, including robust stability, biocompatibility, minimal immunogenicity, and the …

Quaternary structural diversity in eukaryotic DNA polymerases: monomeric to multimeric form

N Acharya, P Khandagale, S Thakur, JK Sahu… - Current genetics, 2020 - Springer
Sixteen eukaryotic DNA polymerases have been identified and studied so far. Based on the
sequence similarity of the catalytic subunits of DNA polymerases, these have been classified …

[HTML][HTML] RanBP2-mediated SUMOylation promotes human DNA polymerase lambda nuclear localization and DNA repair

M Moreno-Oñate, AM Herrero-Ruiz… - Journal of molecular …, 2020 - Elsevier
Cellular DNA is under constant attack by a wide variety of agents, both endogenous and
exogenous. To counteract DNA damage, human cells have a large collection of DNA repair …

Variations in nuclear localization strategies among pol X family enzymes

TW Kirby, LC Pedersen, SA Gabel, NR Gassman… - Traffic, 2018 - Wiley Online Library
Despite the essential roles of pol X family enzymes in DNA repair, information about the
structural basis of their nuclear import is limited. Recent studies revealed the unexpected …

[PDF][PDF] Vliv podchlazení organismu na poškození a reparaci DNA

K Bednářová - 2020 - dspace.cuni.cz
Genetická informace, ukrytá ve všech buňkách, je neustále vystavena působení mnoha
různých faktorů, které ji mohou poškodit. Poškození genetické informace je způsobené …