Contribution of interleukin-17a to retinal degenerative diseases

H Zhong, X Sun - Frontiers in Immunology, 2022 - frontiersin.org
Retinal degenerative diseases are a leading cause of vision loss and blindness throughout
the world, characterized by chronic and progressive loss of neurons and/or myelin. One of …

Aspergillus Endophthalmitis: Epidemiology, Pathobiology, and Current Treatments

A Khambati, RE Wright III, S Das, S Pasula… - Journal of fungi, 2022 - mdpi.com
Fungal endophthalmitis is one of the leading causes of vision loss worldwide. Post-operative
and traumatic injuries are major contributing factors resulting in ocular fungal infections in …

Proteomic profiling of aspergillus flavus endophthalmitis derived extracellular vesicles in an in-vivo murine model

J Gandhi, MN Naik, DK Mishra, J Joseph - Medical Mycology, 2022 - academic.oup.com
Abstract Extracellular Vesicles (EVs) play pivotal roles in cell-to-cell communication, and are
involved in potential pathological and physiological cellular processes. The aim of this study …

Immunopeptides: immunomodulatory strategies and prospects for ocular immunity applications

Y Tang, S Qu, Z Ning, H Wu - Frontiers in Immunology, 2024 - frontiersin.org
Immunopeptides have low toxicity, low immunogenicity and targeting, and broad application
prospects in drug delivery and assembly, which are diverse in application strategies and …

Unveiling the Innate and Adaptive Immunity Interplay: Global Transcriptomic Profiling of the Host Immune Response in Candida albicans Endophthalmitis in a Murine …

A Khapuinamai, D Rudraprasad, S Pandey… - ACS …, 2024 - ACS Publications
Intraocular fungal infection poses a significant clinical challenge characterized by chronic
inflammation along with vision impairment. Understanding the host defense pathways …

Proteomic profiling of extracellular vesicles derived from ARPE-19 cells challenged with Aspergillus flavus and Candida albicans: application in fungal …

J Gandhi, J Joseph - Pathogens and Disease, 2022 - academic.oup.com
Extracellular vesicles (EVs) are nano-sized-particles that play an important role in cellular
cross-talk. The aim of this study was to understand the proteomic cargo of EVs, released by …

Global Transcriptomic Profiling of Innate and Adaptive Immunity During Aspergillus flavus Endophthalmitis in a Murine Model

A Khapuinamai, D Rudraprasad… - … & visual science, 2024 - iovs.arvojournals.org
Purpose: Fungal endophthalmitis is characterized by chronic inflammation leading to the
partial or complete vision loss. Herein, we analyzed the transcriptomic landscape of …