Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Targeting GM-CSF in COVID-19 pneumonia: rationale and strategies

A Bonaventura, A Vecchié, TS Wang, E Lee… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a clinical syndrome ranging from mild symptoms to severe pneumonia that
often leads to respiratory failure, need for mechanical ventilation, and death. Most of the lung …

Therapeutic cancer vaccines: past, present, and future

C Guo, MH Manjili, JR Subjeck, D Sarkar… - Advances in cancer …, 2013 - Elsevier
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …

Cancer immunotherapy: moving beyond current vaccines

SA Rosenberg, JC Yang, NP Restifo - Nature medicine, 2004 - nature.com
Great progress has been made in the field of tumor immunology in the past decade, but
optimism about the clinical application of currently available cancer vaccine approaches is …

Immunotherapy of cancer in 2012

JM Kirkwood, LH Butterfield, AA Tarhini… - CA: a cancer journal …, 2012 - Wiley Online Library
The immunotherapy of cancer has made significant strides in the past few years due to
improved understanding of the underlying principles of tumor biology and immunology …

Cancer vaccines

LH Butterfield - Bmj, 2015 - bmj.com
Cancer vaccines are designed to promote tumor specific immune responses, particularly
cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines …

A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer

G Giaccone, LA Bazhenova, J Nemunaitis… - European journal of …, 2015 - Elsevier
Background Treatment options after first-line chemotherapy are limited in non-small cell lung
cancer (NSCLC). Belagenpumatucel-L is a therapeutic vaccine comprised of 4 transforming …

Dual role of GM-CSF as a pro-inflammatory and a regulatory cytokine: implications for immune therapy

P Bhattacharya, I Budnick, M Singh… - Journal of Interferon & …, 2015 - liebertpub.com
Granulocyte macrophage colony stimulating factor (GM-CSF) is generally recognized as an
inflammatory cytokine. Its inflammatory activity is primarily due its role as a growth and …

Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond

M Farina, JF Alexander, U Thekkedath, M Ferrari… - Advanced drug delivery …, 2019 - Elsevier
Cell-based therapy is emerging as a promising strategy for treating a wide range of human
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …

Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non–small-cell lung cancer

C Butts, N Murray, A Maksymiuk, G Goss… - Journal of Clinical …, 2005 - ascopubs.org
Purpose To evaluate the effect of BLP25 liposome vaccine (L-BLP25) on survival and
toxicity in patients with stage IIIB and IV non–small-cell lung cancer (NSCLC). Secondary …