Cancer is a class of formidable disease with high degree of mortality. Despite much
progress in chemotherapy, the problem of drug resistance has led to the search for newer …

The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is
present in a large number of biologically active molecules, including several drugs currently …

A series of chalcone linked-1, 2, 3-triazoles was synthesized via cellulose supported copper
nanoparticle catalyzed click reaction in water. The structures of all the compounds were …

The selective synthesis of N 2-sulfonyl and N 2-H 1, 2, 3-triazoles via organocatalytic
annulation of enaminone/enaminoester with sulfonyl azide has been realized. The …

A series of 1-substituted benzyl-4-[1-phenyl-3-(4-methyl-2-aryl-1, 3-thiazol-5-yl)-1H-pyrazol-
4-yl]-1H-1, 2, 3-triazole derivatives (7a-y) have been synthesized by click reaction of 5-(4 …

An efficient, green strategy for synthesis of 1, 4-disubstituted-1, 2, 3-triazole has been
developed using 1, 8-diazabicyclo [5.4. 0] undec-7-ene (DBU) acetate ionic liquid (200 μL) …

In this work we aimed to perform an in silico predictive screening, docking and molecular
dynamic study to identify 1, 2, 3-triazole-phthalimide derivatives as drug candidates against …

The concept of click chemistry represented by the formation of the 1, 2, 3-triazole core has
found wide application in drug discovery, particularly in the early discovery phases and the …

Abstract A diverse series of 4-((1-benzyl/phenyl-1 H-1, 2, 3-triazol-4-yl) methoxy)
benzaldehyde analogues has been synthesized in good yield by the click reaction between …

Sixteen 1, 4-diaryl-1, 2, 3-triazole compounds derived from the natural products
veraguensin, grandisin and machilin G were synthesized, with yields of 78-92%. Biological …