Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns

DEW Chatterton, DN Nguyen, SB Bering… - The international journal …, 2013 - Elsevier
The human newborn infant is susceptible to gut inflammatory disorders. In particular, growth-
restricted infants or infants born prematurely may develop a severe form of intestinal …

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

ES Van Amersfoort, TJC Van Berkel… - Clinical microbiology …, 2003 - Am Soc Microbiol
Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

Lactoferrin as a natural immune modulator

JK Actor, SA Hwang, ML Kruzel - Current pharmaceutical …, 2009 - ingentaconnect.com
Lactoferrin, an iron-binding glycoprotein, is a cell-secreted mediator that bridges innate and
adaptive immune function in mammals. It is a pleiotropic molecule that directly assists in the …

Lactoferrin: Mammalian lactoferrin receptors: structure and function

YA Suzuki, V Lopez, B Lönnerdal - Cellular and Molecular Life Sciences, 2005 - Springer
Mammalian lactoferrin (Lf) receptors are suggested to have pivotal roles for mediating
multiple functions of Lf. In this review, we focus on current knowledge of the structure and …

Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-κB

L Håversen, BG Ohlsson, M Hahn-Zoric, LÅ Hanson… - Cellular …, 2002 - Elsevier
Lactoferrin, a glycoprotein present in milk, mucosal secretions and neutrophils contributes to
host defense. We have previously shown that orally given milk lactoferrin (LF) mediates anti …

Lactoferrin Is a Potent Regulator of Bone Cell Activity and Increases Bone Formation in Vivo

J Cornish, KE Callon, D Naot, KP Palmano… - …, 2004 - academic.oup.com
Altered expression of the TGF-β system is recognized to play a central role in various fibrotic
disorders, including leiomyoma. In this study we performed microarray analysis to …

Lactoferrin, a pleiotropic protein in health and disease

S Mayeur, S Spahis, Y Pouliot, E Levy - Antioxidants & redox …, 2016 - liebertpub.com
Abstract Significance: Lactoferrin (Lf) is a nonheme iron-binding glycoprotein strongly
expressed in human and bovine milk and it plays many functions during infancy such as iron …

Lactoferrin structure and functions

D Legrand, A Pierce, E Elass, M Carpentier… - Bioactive components of …, 2008 - Springer
Lactoferrin (Lf) is an iron binding glycoprotein of the transferrin family that is expressed in
most biological fluids and is a major component of mammals' innate immune system. Its …

The impact of metal availability on immune function during infection

AJ Monteith, EP Skaar - Trends in Endocrinology & Metabolism, 2021 - cell.com
Nutrient transition metals are required cofactors for many proteins to perform functions
necessary for life. As such, the concentration of nutrient metals is carefully maintained to …

Lactoferrin and host defense

PP Ward, S Uribe-Luna… - Biochemistry and Cell …, 2002 - cdnsciencepub.com
La lactoferrine est une protéine multifonctionnelle faisant partie de la famille de la
transferrine et des glycoprotéines liant le fer non hémique. La lactoferrine se trouve à la …