Enzymes and their regulations are employed as indicators for various diseases, including
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …

Identification of bacterial strains is critical for the theranostics of bacterial infections and the
development of antibiotics. Many organic fluorescent probes have been developed to …

Diabetic wound is one of the most intractable chronic wounds that is prone to bacterial
infection. Hypoxia is an important feature in its microenvironment. However, it is challenging …

Bacterial infections remain a global healthcare problem that is particularly attributed to the
spread of antibiotic resistance and the evolving pathogenicity. Accurate and swift …

The fluorescence imaging technique has attracted increasing attention in the detection of
various biological molecules in situ and in real-time owing to its inherent advantages …

As one of the most representative hypoxic enzymes, nitroreductases (NTRs) play
momentous roles in malignant tumor progression, metastasis, invasion and angiogenesis …

Fluorescent probe technology has been widely used in biochemistry, medicine,
environmental science and industry. Resorufin has been widely used in the design of small …

The over-expressed nitroreductase (NTR) is a common biomarker of tumor hypoxia. Thus,
achieving sensitive and accurate detection of NTR is significant for the guidance of tumor …

Ulcerative colitis, a kind of inflammatory bowel disease (IBD), is caused by dysregulated
immune response of intestinal bacteria. This chronic disorder can lead to a deficiency of O 2 …

The majority of nosocomial infections are caused by bacteria with antimicrobial resistance
and the formation of biofilms, such as implant-related bacterial infections and sepsis. There …