Clostridium difficile is the main causative agent of antibiotic-associated and health care-
associated infective diarrhea. Recently, there has been growing interest in alternative …

Although largely deprived from exogenous stimuli in utero, the mucosal barriers of the
neonate after birth are bombarded by environmental, nutritional, and microbial exposures …

Background & Aims Few studies, even those with cohort designs, test the mediating effects
of infant gut microbes and metabolites on the onset of disease. We undertook such a study …

There has been an increase in the prevalence of Clostridioides difficile (C. diff) causing
significant economic impact on the health care system. Although toxigenic C. diff carriage is …

Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is
responsible for many healthcare-associated infections, such as nosocomial diarrhea …

Clostridium difficile (C. difficile) is a spore-forming, toxin-producing, gram-positive anaerobic
bacterium that is the principal etiologic agent of antibiotic-associated diarrhea. Infection with …

Importance Detection ofClostridioides difficilehas frequently been described in
asymptomatic infants and children, but accurate estimates across the age spectrum are …

The pathogenic Clostridioides difficile and Clostridium perfringens are responsible for many
health care-associated infections as well as systemic and enteric diseases. Therefore, they …

Background The fecal microbiota, fecal bile acid concentrations, and abundance of
Clostridium perfringens and Clostridium difficile are altered in acute and chronic …

Background Since 2008, Danish national surveillance of Clostridioides difficile has focused
on binary toxin-positive strains in order to monitor epidemic types such as PCR ribotype (RT) …