Silver nanoparticles: their potential toxic effects after oral exposure and underlying mechanisms–a review

S Gaillet, JM Rouanet - Food and Chemical Toxicology, 2015 - Elsevier
Because of their antimicrobial properties, the use of silver nanoparticles (AgNPs) is
increasing fast in industry, food, and medicine. In the food industry, nanoparticles are used …

Paraoxonase and atherosclerosis

PN Durrington, B Mackness… - … , thrombosis, and vascular …, 2001 - Am Heart Assoc
There is considerable evidence that the antioxidant activity of high density lipoprotein (HDL)
is largely due to the paraoxonase-1 (PON1) located on it. Experiments with transgenic PON1 …

HDL function and atherosclerosis: reactive dicarbonyls as promising targets of therapy

MRF Linton, PG Yancey, H Tao, SS Davies - Circulation research, 2023 - Am Heart Assoc
Epidemiologic studies detected an inverse relationship between HDL (high-density
lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease …

Modulation of paraoxonase (PON1) activity

LG Costa, A Vitalone, TB Cole, CE Furlong - Biochemical pharmacology, 2005 - Elsevier
Paraoxonase 1 (PON1) is a serum enzyme closely associated with high density lipoprotein
(HDL). PON1 hydrolyzes several organophosphorus compounds used as insecticides, as …

HDL and arteriosclerosis: beyond reverse cholesterol transport

JR Nofer, B Kehrel, M Fobker, B Levkau, G Assmann… - Atherosclerosis, 2002 - Elsevier
The inverse correlation between serum levels of high density lipoprotein (HDL) cholesterol
and the risk of coronary heart disease, the protection of susceptible animals from …

Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype?

B Mackness, GK Davies, W Turkie, E Lee… - … , and vascular biology, 2001 - Am Heart Assoc
Human serum paraoxonase (PON1) hydrolyzes oxidized lipids in low density lipoprotein
(LDL) and could therefore retard the development of atherosclerosis. In keeping with this …

[HTML][HTML] Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of …

M Kaplan, T Hayek, A Raz, R Coleman, L Dornfeld… - The Journal of …, 2001 - Elsevier
Inhibition of lipid peroxidation contributes to the attenuation of macrophage cholesterol
accumulation, foam-cell formation and atherosclerosis. Evidence suggests that nutritional …

The paraoxonases: role in human diseases and methodological difficulties in measurement

J Camps, J Marsillach, J Joven - Critical reviews in clinical …, 2009 - Taylor & Francis
Research into the paraoxonase (PON) gene family has flourished over the past few years. In
the 1970s and 1980s, only PON1 was known, and the investigations were conducted …

The paraoxonase gene family and atherosclerosis

CJ Ng, DM Shih, SY Hama, N Villa, M Navab… - Free radical biology and …, 2005 - Elsevier
Epidemiologic, genetic, and biochemical studies support an antiatherogenic role for
paraoxonase (PON) 1. While the precise mechanism by which PON1 protects against the …

How high-density lipoprotein protects against the effects of lipid peroxidation

MI Mackness, PN Durrington… - Current opinion in …, 2000 - journals.lww.com
The protective effect of HDL against the development of atherosclerosis appears to be
multifaceted involving a number of mechanisms. One of the major mechanisms is, however …