Endothelium in vitro: a review of human vascular endothelial cell lines for blood vessel-related research

D Bouïs, GAP Hospers, C Meijer, G Molema… - Angiogenesis, 2001 - Springer
Endothelial cells (EC) are currently used as in vitro model systems for various physiological
and pathological processes, especially in angiogenesis research. Primary EC have a limited …

[HTML][HTML] Vascular inflammation on a chip: A scalable platform for trans-endothelial electrical resistance and immune cell migration

H Ehlers, A Nicolas, F Schavemaker… - Frontiers in …, 2023 - frontiersin.org
The vasculature system plays a critical role in inflammation processes in the body. Vascular
inflammatory mechanisms are characterized by disruption of blood vessel wall permeability …

In vitro expression of the endothelial phenotype: comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1. 6R

RE Unger, V Krump-Konvalinkova, K Peters… - Microvascular …, 2002 - Elsevier
Endothelial cell lines are commonly used in in vitro studies to avoid problems associated
with the use of primary endothelial cells such as the presence of contaminating cells, the …

[HTML][HTML] A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA. hy926 endothelial cell line

E Aranda, GI Owen - Biological research, 2009 - SciELO Chile
Angiogenesis, the development of new capillary vessels, has a host of clinical
manifestations. The identification of agents that increase or decrease angiogenesis is of …

A comparison of primary endothelial cells and endothelial cell lines for studies of immune interactions

EA Lidington, DL Moyes, AM McCormack… - Transplant immunology, 1999 - Elsevier
The purpose of this study was to assess the suitability of using endothelial cell (EC) lines for
studies of endothelial/immune interactions. The immortal human EC lines HMEC-1, ECV304 …

Interferon-γ and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function

T Oshima, FS Laroux, LL Coe, Z Morise, S Kawachi… - Microvascular …, 2001 - Elsevier
Inflammatory bowel disease (IBD) is associated with Th1/Th2 cytokine dysregulation,
leukocyte extravasation, and tissue edema, but the mechanisms for cytokine-mediated …

PPARα and PPARδ activators inhibit cytokine-induced nuclear translocation of NF-κB and expression of VCAM-1 in EAhy926 endothelial cells

Y Rival, N Benéteau, T Taillandier, M Pezet… - European journal of …, 2002 - Elsevier
Endothelium injury is a primary event in atherogenesis, which is followed by monocyte
infiltration, macrophage differentiation, and smooth muscle cell migration. Peroxisome …

Mononuclear cell adhesion and cell adhesion molecule liberation after X-irradiation of activated endothelial cells in vitro

G Hildebrandt, L Maggiorella, F Rödel… - … journal of radiation …, 2002 - Taylor & Francis
Purpose: Increased expression of cell adhesion molecules on endothelial cells is an
important early event in inflammation. Low-dose radiotherapy is very effective anti …

[HTML][HTML] Antioxidant and anti-inflammatory effects of Astragalus polysaccharide on EA. hy926 cells

WM Huang, YQ Liang, LJ Tang… - Experimental and …, 2013 - spandidos-publications.com
The aim of this study was to explore the role of astragalus polysaccharide (APS) in the
pathogenesis of bronchopulmonary dysplasia (BPD) in preterm children using an …

Gene delivery by dendrimers operates via a cholesterol dependent pathway

M Manunta, PH Tan, P Sagoo, K Kashefi… - Nucleic acids …, 2004 - academic.oup.com
Understanding the cellular uptake and intracellular trafficking of dendrimer–DNA complexes
is an important prerequisite for improving the transfection efficiency of non‐viral vector …