Ultrasound as a versatile tool for short-and long-term improvement and monitoring of brain function
DG Blackmore, D Razansky, J Götz - Neuron, 2023 - cell.com
Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …
Physical mechanisms of emerging neuromodulation modalities
One of the ultimate goals of neurostimulation field is to design materials, devices and
systems that can simultaneously achieve safe, effective and tether-free operation. For that …
systems that can simultaneously achieve safe, effective and tether-free operation. For that …
Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology
Focused ultrasound can non-invasively modulate neural activity, but whether effective
stimulation parameters generalize across brain regions and cell types remains unknown …
stimulation parameters generalize across brain regions and cell types remains unknown …
Device for multifocal delivery of ultrasound into deep brain regions in humans
Low-intensity focused ultrasound provides the means to noninvasively stimulate or release
drugs in specified deep brain targets. However, successful clinical translations require …
drugs in specified deep brain targets. However, successful clinical translations require …
[HTML][HTML] High-throughput ultrasound neuromodulation in awake and freely behaving rats
Transcranial ultrasound neuromodulation is a promising potential therapeutic tool for the
noninvasive treatment of neuropsychiatric disorders. However, the expansive parameter …
noninvasive treatment of neuropsychiatric disorders. However, the expansive parameter …
[HTML][HTML] Sustained modulation of primate deep brain circuits with focused ultrasonic waves
Background Transcranial focused ultrasound has the potential to noninvasively modulate
deep brain circuits and impart sustained, neuroplastic effects. Objective Bring the approach …
deep brain circuits and impart sustained, neuroplastic effects. Objective Bring the approach …
[HTML][HTML] Modulation effects of low-intensity transcranial ultrasound stimulation on the neuronal firing activity and synaptic plasticity of mice
Z Zhao, H Ji, C Zhang, J Pei, X Zhang, Y Yuan - Neuroimage, 2023 - Elsevier
Low-intensity transcranial ultrasound stimulation (TUS) has been effective in modulating
several neurological and psychiatric disorders. However, how TUS modulates neuronal …
several neurological and psychiatric disorders. However, how TUS modulates neuronal …
Durable effects of deep brain ultrasonic neuromodulation on major depression: a case report
Background Severe forms of depression have been linked to hyperactivity of the subcallosal
cingulate cortex. The ability to stimulate the subcallosal cingulate cortex or associated …
cingulate cortex. The ability to stimulate the subcallosal cingulate cortex or associated …
[HTML][HTML] Low-intensity focused ultrasound to the posterior insula reduces temporal summation of pain
A In, A Strohman, B Payne, W Legon - Brain stimulation, 2024 - Elsevier
Background The insula and dorsal anterior cingulate cortex (dACC) are core brain regions
involved in pain processing and central sensitization, a shared mechanism across various …
involved in pain processing and central sensitization, a shared mechanism across various …
Effects of focused ultrasound pulse duration on stimulating cortical and subcortical motor circuits in awake sheep
Low-intensity transcranial focused ultrasound (tFUS) offers new functional neuromodulation
opportunities, enabling stimulation of cortical as well as deep brain areas with high spatial …
opportunities, enabling stimulation of cortical as well as deep brain areas with high spatial …